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MYC-xing it up with PIK3CA mutation and resistance to PI3K inhibitors: summit of two giants in breast cancers

Approximately 35% of breast cancers exhibit PIK3CA activating mutation. Since PIK3CA hotspot mutation is the most frequently mutated gene in human breast cancers and primarily overlaps in HER2+ as well as ER+ breast cancers, the subset of patients bearing PIK3CA activating mutation does not get full...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Am J Cancer Res
मुख्य लेखकों: Dey, Nandini, Leyland-Jones, Brian, De, Pradip
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: e-Century Publishing Corporation 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300701/
https://ncbi.nlm.nih.gov/pubmed/25628917
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