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Role of “oncogenic nexus” of CIP2A in breast oncogenesis: how does it work?

The CIP2A gene is an oncogene associated with solid and hematologic malignancies [1]. CIP2A protein is an oncoprotein and a potential cancer therapy target [2]. Literature shows that CIP2A inhibits the tumor suppressor protein PP2A [3] which downregulates phophorylation of AKT, a hallmark of cancers...

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Bibliografske podrobnosti
izdano v:Am J Cancer Res
Main Authors: De, Pradip, Carlson, Jennifer H, Leyland-Jones, Brian, Dey, Nandini
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633914/
https://ncbi.nlm.nih.gov/pubmed/26609493
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