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Role of “oncogenic nexus” of CIP2A in breast oncogenesis: how does it work?
The CIP2A gene is an oncogene associated with solid and hematologic malignancies [1]. CIP2A protein is an oncoprotein and a potential cancer therapy target [2]. Literature shows that CIP2A inhibits the tumor suppressor protein PP2A [3] which downregulates phophorylation of AKT, a hallmark of cancers...
Shranjeno v:
izdano v: | Am J Cancer Res |
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Main Authors: | , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
e-Century Publishing Corporation
2015
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4633914/ https://ncbi.nlm.nih.gov/pubmed/26609493 |
Oznake: |
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