RAC1 GTP-ase signals Wnt-beta-catenin pathway mediated integrin-directed metastasis-associated tumor cell phenotypes in triple negative breast cancers

The acquisition of integrin-directed metastasis-associated (ID-MA) phenotypes by Triple-Negative Breast Cancer (TNBC) cells is caused by an upregulation of the Wnt-beta-catenin pathway (WP). We reported that WP is one of the salient genetic features of TNBC. RAC-GTPases, small G-proteins which trans...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: De, Pradip, Carlson, Jennifer H., Jepperson, Tyler, Willis, Scooter, Leyland-Jones, Brian, Dey, Nandini
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356866/
https://ncbi.nlm.nih.gov/pubmed/27902969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13618
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