Xenobiotics and Autoimmunity: Does Acetaminophen Cause Primary Biliary Cirrhosis?

Por Leung, Patrick S.C., Lam, Kit, Kurth, Mark J., Coppel, Ross L., Gershwin, M. Eric
Publicado em 2012

Is there a Relation between Chlamydia Infection and Primary Biliary Cirrhosis?

Por Leung, Patrick S. C., Park, Ogyi, Matsumura, Shuji, Ansari, Aftab A., Coppel, Ross L., Gershwin, M. Eric
Publicado em 2003

A contemporary perspective on the molecular characteristics of mitochondrial autoantigens and diagnosis in primary biliary cholangitis

Por Leung, Patrick S.C., Choi, Jinjung, Yang, Guoxiang, Woo, Elena, Kenny, Thomas P., Gershwin, M. Eric
Publicado no Expert Rev Mol Diagn (2016)

Innate Immunity Drives the Initiation of a Murine Model of Primary Biliary Cirrhosis

Por Chang, Chao-Hsuan, Chen, Ying-Chun, Zhang, Weici, Leung, Patrick S. C., Gershwin, M. Eric, Chuang, Ya-Hui
Publicado no PLoS One (2015)

Environment and Primary Biliary Cirrhosis: Electrophilic Drugs and the Induction of AMA

Por Leung, Patrick S.C., Wang, Jinjun, Naiyanetr, Phornnop, Kenny, Thomas P., Lam, Kit S., Kurth, Mark J., Gershwin, M. Eric
Publicado em 2013

Innate immunity and PBC: Activated invariant NKT cells exacerbate murine autoimmune cholangitis and fibrosis

Por Wu, Si-Jie, Yang, Yao-Hsu, Tsuneyama, Koichi, Leung, Patrick S.C., Illarionov, Petr, Gershwin, M. Eric, Chuang, Ya-Hui
Publicado em 2011

Primary Biliary Cirrhosis and the Nuclear Pore Complex

Por Duarte-Rey, Carolina, Bogdanos, Dimitrios, Yang, Chen-Yen, Roberts, Krista, Leung, Patrick S.C., Anaya, Juan-Manuel, Worman, Howard J., Gershwin, M. Eric
Publicado em 2012

Immunization with Hypoallergens of Shrimp Allergen Tropomyosin Inhibits Shrimp Tropomyosin Specific IgE Reactivity

Por Wai, Christine Y. Y., Leung, Nicki Y. H., Ho, Marco H. K., Gershwin, Laurel J., Shu, Shang An, Leung, Patrick S. C., Chu, Ka Hou
Publicado no PLoS One (2014)

Deletion of Galectin-3 Enhances Xenobiotic Induced Murine Primary Biliary Cholangitis by Facilitating Apoptosis of BECs and Release of Autoantigens

Por Arsenijevic, Aleksandar, Milovanovic, Marija, Milovanovic, Jelena, Stojanovic, Bojana, Zdravkovic, Natasa, Leung, Patrick S.C., Liu, Fu-Tong, Gershwin, M. Eric, Lukic, Miodrag L.
Publicado no Sci Rep (2016)

Criteria for Environmentally Associated Autoimmune Diseases

Por Miller, Frederick W., Pollard, K. Michael, Parks, Christine G., Germolec, Dori R., Leung, Patrick S.C., Selmi, Carlo, Humble, Michael C., Rose, Noel R.
Publicado em 2012

Antimitochondrial Antibodies in Acute Liver Failure: Implications for Primary Biliary Cirrhosis

Por Leung, Patrick S.C., Rossaro, Lorenzo, Davis, Paul A., Park, Ogyi, Tanaka, Atsushi, Kikuchi, Kentaro, Miyakawa, Hiroshi, Norman, Gary L., Lee, William, Gershwin, M. Eric
Publicado em 2007

Cross-talk between Aryl Hydrocarbon Receptor and the Inflammatory Response: A ROLE FOR NUCLEAR FACTOR-κB

Por Vogel, Christoph F. A., Khan, Elaine M., Leung, Patrick S. C., Gershwin, M. Eric, Chang, W. L. William, Wu, Dalei, Haarmann-Stemmann, Thomas, Hoffmann, Alexander, Denison, Michael S.
Publicado em 2014

Autoimmune Acute Liver Failure: Proposed Clinical and Histological Criteria

Por Stravitz, R. Todd, Lefkowitch, Jay H., Fontana, Robert J., Gershwin, M. Eric, Leung, Patrick S.C., Sterling, Richard K., Manns, Michael P., Norman, Gary L., Lee, William M.
Publicado em 2011

Murine autoimmune cholangitis requires two hits: Cytotoxic KLRG1(+) CD8 effector cells and defective T regulatory cells

Por Huang, Wenting, Kachapati, Kritika, Adams, David, Wu, Yuehong, Leung, Patrick S.C., Yang, Guo-Xiang, Zhang, Weici, Ansari, Aftab A., Flavell, Richard A., Gershwin, M. Eric, Ridgway, William M.
Publicado em 2014

Characterization and Epitope Mapping of Human Monoclonal Antibodies to PDC-E2, the Immunodominant Autoantigen of Primary Biliary Cirrhosis

Por Leung, Patrick S. C., Krams, Sheri, Munoz, Santiago, Surh, Charles P., Ansari, Aftab, Kenny, Thomas, Robbins, Dick L., Fung, John, Starzl, Thomas E., Maddrey, Willis, Coppel, Ross L., Gershwin, M. Eric
Publicado em 1992

NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis

Por Irie, Junichiro, Wu, Yuehong, Wicker, Linda S., Rainbow, Daniel, Nalesnik, Michael A., Hirsch, Raphael, Peterson, Laurence B., Leung, Patrick S.C., Cheng, Chunmei, Mackay, Ian R., Gershwin, M. Eric, Ridgway, William M.
Publicado em 2006

Lymphoma-Like T Cell Infiltration in Liver Is Associated with Increased Copy Number of Dominant Negative Form of TGFβ Receptor II

Por Zhang, Weici, Tsuda, Masanobu, Yang, Guo-Xiang, Tsuneyama, Koichi, He, Xiao-Song, Ansari, Aftab A., Ridgway, William M., Coppel, Ross L., Lian, Zhe-Xiong, Leung, Patrick S.C., Gershwin, M. Eric
Publicado em 2012

SHOTGUN PROTEOMICS: IDENTIFICATION OF UNIQUE PROTEIN PROFILES OF APOPTOTIC BODIES FROM BILIARY EPITHELIAL CELLS

Por Lleo, Ana, Zhang, Weici, McDonald, W. Hayes, Seeley, Erin H., Leung, Patrick S.C., Coppel, Ross L., Ansari, Aftab A., Adams, David H., Afford, Simon, Invernizzi, Pietro, Gershwin, M. Eric
Publicado em 2014

Transgenic Overexpression of Aryl Hydrocarbon Receptor Repressor (AhRR) and AhR-Mediated Induction of CYP1A1, Cytokines, and Acute Toxicity

Por Vogel, Christoph F.A., Chang, W.L. William, Kado, Sarah, McCulloh, Kelly, Vogel, Helena, Wu, Dalei, Haarmann-Stemmann, Thomas, Yang, GuoXiang, Leung, Patrick S.C., Matsumura, Fumio, Gershwin, M. Eric
Publicado no Environ Health Perspect (2016)

Clonality, Activated Antigen Specific CD8(+) T Cells and Development of Autoimmune Cholangitis in dnTGFβRII Mice

Por Kawata, Kazuhito, Yang, Guo-Xiang, Ando, Yugo, Tanaka, Hajime, Zhang, Weici, Kobayashi, Yoshimasa, Tsuneyama, Koichi, Leung, Patrick S.C., Lian, Zhe-Xiong, Ridgway, William M., Ansari, Aftab A., He, Xiao-Song, Gershwin, M. Eric
Publicado em 2013