Immunization with Hypoallergens of Shrimp Allergen Tropomyosin Inhibits Shrimp Tropomyosin Specific IgE Reactivity

Designer proteins deprived of its IgE-binding reactivity are being sought as a regimen for allergen-specific immunotherapy. Although shrimp tropomyosin (Met e 1) has long been identified as the major shellfish allergen, no immunotherapy is currently available. In this study, we aim at identifying th...

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Pubblicato in:PLoS One
Autori principali: Wai, Christine Y. Y., Leung, Nicki Y. H., Ho, Marco H. K., Gershwin, Laurel J., Shu, Shang An, Leung, Patrick S. C., Chu, Ka Hou
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218792/
https://ncbi.nlm.nih.gov/pubmed/25365343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111649
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