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Xenobiotics and Autoimmunity: Does Acetaminophen Cause Primary Biliary Cirrhosis?
The serologic hallmark of primary biliary cirrhosis (PBC) is the presence of antimitochondrial autoantibodies (AMA) directed against the E2 subunit of PDC-E2. The PBC-related autoepitope of PDC-E2 contains lipoic acid, and previous work has demonstrated that mimics of lipoic acid following immunizat...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465509/ https://ncbi.nlm.nih.gov/pubmed/22920894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.07.005 |
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