Novel therapeutic target against Alzheimer

Por LeBlanc, Andrea C.
Publicado no Oncotarget (2017)

Luman contributes to brefeldin A-induced prion protein gene expression by interacting with the ERSE26 element

Por Déry, Marc-André, LeBlanc, Andréa C.
Publicado no Sci Rep (2017)

Cyclin-dependent Kinase 5 Phosphorylation of Familial Prion Protein Mutants Exacerbates Conversion into Amyloid Structure

Por Rouget, Raphaël, Sharma, Gyanesh, LeBlanc, Andréa C.
Publicado no J Biol Chem (2015)

HELIX 3 IS NECESSARY AND SUFFICIENT FOR PRION PROTEIN’S ANTI-BAX FUNCTION

Por Laroche-Pierre, Stéphanie, Jodoin, Julie, LeBlanc, Andréa C.
Publicado em 2009

Familial prion protein mutants inhibit Hrd1-mediated retrotranslocation of misfolded proteins by depleting misfolded protein sensor BiP

Por Peters, Sarah L., Déry, Marc-André, LeBlanc, Andrea C.
Publicado no Hum Mol Genet (2016)

Targets of Caspase-6 Activity in Human Neurons and Alzheimer Disease

Por Klaiman, Guy, Petzke, Tracy L., Hammond, Jennifer, LeBlanc, Andréa C.
Publicado em 2008

Caspase-6 Activation in Familial Alzheimer Disease Brains Carrying Amyloid Precursor Protein, Presenilin I or Presenilin II Mutations

Por Albrecht, Steffen, Bogdanovic, Nenad, Ghetti, Bernardino, Winblad, Bengt, LeBlanc, Andréa C.
Publicado em 2009

Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine

Por Pakavathkumar, Prateep, Sharma, Gyanesh, Kaushal, Vikas, Foveau, Bénédicte, LeBlanc, Andrea C.
Publicado no Sci Rep (2015)

CYTOSOLIC PRION PROTEIN IS THE PREDOMINANT ANTI-BAX PRION PROTEIN FORM: EXCLUSION OF TRANSMEMBRANE AND SECRETED PRION PROTEIN FORMS IN THE ANTI-BAX FUNCTION

Por Lin, David T. S., Jodoin, Julie, Baril, Michaël, Goodyer, Cynthia G., LeBlanc, Andréa C.
Publicado em 2008

Expression and Activation of Caspase-6 in Human Fetal and Adult Tissues

Por Godefroy, Nelly, Foveau, Bénédicte, Albrecht, Steffen, Goodyer, Cynthia G., LeBlanc, Andréa C.
Publicado em 2013

Active Caspase-6 and Caspase-6-Cleaved Tau in Neuropil Threads, Neuritic Plaques, and Neurofibrillary Tangles of Alzheimer’s Disease

Por Guo, Huishan, Albrecht, Steffen, Bourdeau, Martine, Petzke, Tracy, Bergeron, Catherine, LeBlanc, Andrea C.
Publicado em 2004

Caspase-6 activity predicts lower episodic memory ability in aged individuals

Por Ramcharitar, Jasmine, Afonso, Veronica M., Albrecht, Steffen, Bennett, David A., LeBlanc, Andrea C.
Publicado em 2013

Inflammation-Induced Tumorigenesis in Mouse Colon Is Caspase-6 Independent

Por Foveau, Bénédicte, Van Der Kraak, Lauren, Beauchemin, Nicole, Albrecht, Steffen, LeBlanc, Andréa C.
Publicado no PLoS One (2014)

Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment

Por Foveau, Benedicte, Albrecht, Steffen, Bennett, David A., Correa, José A., LeBlanc, Andrea C.
Publicado no Acta Neuropathol Commun (2016)

Activation of Caspase-6 in Aging and Mild Cognitive Impairment

Por Albrecht, Steffen, Bourdeau, Martine, Bennett, David, Mufson, Elliott J., Bhattacharjee, Meena, LeBlanc, Andréa C.
Publicado em 2007

Identification of Caspase-6-Mediated Processing of the Valosin Containing Protein (p97) in Alzheimer's Disease: A Novel Link to Dysfunction in Ubiquitin Proteasome System-Mediated...

Por Halawani, Dalia, Tessier, Sylvain, Anzellotti, Dominique, Bennett, David A., Latterich, Martin, LeBlanc, Andréa C.
Publicado em 2010

Identification of a Novel Endoplasmic Reticulum Stress Response Element Regulated by XBP1

Por Misiewicz, Michael, Déry, Marc-André, Foveau, Bénédicte, Jodoin, Julie, Ruths, Derek, LeBlanc, Andréa C.
Publicado em 2013

Hereditary Inclusion Body Myopathy-Linked p97/VCP Mutations in the NH(2) Domain and the D1 Ring Modulate p97/VCP ATPase Activity and D2 Ring Conformation

Por Halawani, Dalia, LeBlanc, Andréa C., Rouiller, Isabelle, Michnick, Stephen W., Servant, Marc J., Latterich, Martin
Publicado em 2009

Phosphorylation of Prion Protein at Serine 43 Induces Prion Protein Conformational Change

Por Giannopoulos, Paresa N., Robertson, Catherine, Jodoin, Julie, Paudel, Hemant, Booth, Stephanie A., LeBlanc, Andrea C.
Publicado em 2009

Alternatively Spliced Caspase-6B Isoform Inhibits the Activation of Caspase-6A

Por Lee, Andrea W., Champagne, Nathalie, Wang, Xiaojun, Su, Xiao-Dong, Goodyer, Cynthia, LeBlanc, Andrea C.
Publicado em 2010