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Targets of Caspase-6 Activity in Human Neurons and Alzheimer Disease
Caspase-6 activation occurs early in Alzheimer disease and sometimes precedes the clinical manifestation of the disease in aged individuals. The active Caspase-6 is localized in neuritic plaques, in neuropil threads, and in neurofibrillary tangles containing neurons that are not morphologically apop...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2500235/ https://ncbi.nlm.nih.gov/pubmed/18487604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800007-MCP200 |
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