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Targets of Caspase-6 Activity in Human Neurons and Alzheimer Disease

Caspase-6 activation occurs early in Alzheimer disease and sometimes precedes the clinical manifestation of the disease in aged individuals. The active Caspase-6 is localized in neuritic plaques, in neuropil threads, and in neurofibrillary tangles containing neurons that are not morphologically apop...

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Hlavní autoři: Klaiman, Guy, Petzke, Tracy L., Hammond, Jennifer, LeBlanc, Andréa C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2500235/
https://ncbi.nlm.nih.gov/pubmed/18487604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800007-MCP200
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