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Selective and Protracted Apoptosis in Human Primary Neurons Microinjected with Active Caspase-3, -6, -7, and -8

We have shown previously that caspase-6 is activated in serum deprivation-mediated human neuronal cell death and correlates with increased production of Alzheimer's disease (AD) amyloid β peptide (Aβ). Here, we show by direct microinjection of recombinant active enzymes that caspase-6 (>0.5...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhang, Yan, Goodyer, Cynthia, LeBlanc, Andréa
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773170/
https://ncbi.nlm.nih.gov/pubmed/11069945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-22-08384.2000
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