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Alternatively Spliced Caspase-6B Isoform Inhibits the Activation of Caspase-6A

Caspase-6 (Casp6) is activated early in Alzheimer disease and involved in axonal degeneration, but the regulation of Casp6 activity has not been explored. Several alternatively spliced forms of caspases act as inhibitors of caspase activation. The CASP6 gene generates an alternatively spliced transc...

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Detalles Bibliográficos
Main Authors: Lee, Andrea W., Champagne, Nathalie, Wang, Xiaojun, Su, Xiao-Dong, Goodyer, Cynthia, LeBlanc, Andrea C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952198/
https://ncbi.nlm.nih.gov/pubmed/20682790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.152744
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