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HELIX 3 IS NECESSARY AND SUFFICIENT FOR PRION PROTEIN’S ANTI-BAX FUNCTION
To identify the structural elements of the prion protein (PrP) necessary for its protective function against Bax, we performed structure-function analyses of the anti-Bax function of cytosolic PrP (CyPrP) in MCF-7 cells. Deletions of 1, 2, or 3 N-terminal BH2-like octapeptide repeats (BORs), but not...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710996/ https://ncbi.nlm.nih.gov/pubmed/19196429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05851.x |
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