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Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment

Abnormally elevated hippocampal Caspase-6 (Casp6) activity is intimately associated with age-related cognitive impairment in humans and in mice. In humans, these high levels of Casp6 activity are initially localized in the entorhinal cortex, the area of the brain first affected by the formation of n...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Foveau, Benedicte, Albrecht, Steffen, Bennett, David A., Correa, José A., LeBlanc, Andrea C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146837/
https://ncbi.nlm.nih.gov/pubmed/27931265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0400-x
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