Deregulation of Drosha in the pathogenesis of hereditary hemorrhagic telangiectasia

por Hata, Akiko, Lagna, Giorgio
Publicado no Curr Opin Hematol (2019)

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

por Hata, Akiko, Lagna, Giorgio, Massagué, Joan, Hemmati-Brivanlou, Ali
Publicado em 1998

SMAD proteins control DROSHA-mediated microRNA maturation

por Davis, Brandi N., Hilyard, Aaron C., Lagna, Giorgio, Hata, Akiko
Publicado em 2008

Induction of MicroRNA-221 by Platelet-derived Growth Factor Signaling Is Critical for Modulation of Vascular Smooth Muscle Phenotype

por Davis, Brandi N., Hilyard, Aaron C., Nguyen, Peter H., Lagna, Giorgio, Hata, Akiko
Publicado em 2009

Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha

por Davis, Brandi N., Hilyard, Aaron C., Nguyen, Peter H., Lagna, Giorgio, Hata, Akiko
Publicado em 2010

The Four-and-a-half LIM Domain Protein 2 Regulates Vascular Smooth Muscle Phenotype and Vascular Tone

por Neuman, Nicole A., Ma, Susan, Schnitzler, Gavin R., Zhu, Yan, Lagna, Giorgio, Hata, Akiko
Publicado em 2009

Control of Phenotypic Plasticity of Smooth Muscle Cells by Bone Morphogenetic Protein Signaling through the Myocardin-related Transcription Factors()

por Lagna, Giorgio, Ku, Manching M., Nguyen, Peter H., Neuman, Nicole A., Davis, Brandi N., Hata, Akiko
Publicado em 2007

Inhibition of MicroRNA-302 (miR-302) by Bone Morphogenetic Protein 4 (BMP4) Facilitates the BMP Signaling Pathway

por Kang, Hara, Louie, Justin, Weisman, Alexandra, Sheu-Gruttadauria, Jessica, Davis-Dusenbery, Brandi N., Lagna, Giorgio, Hata, Akiko
Publicado em 2012

A Novel Regulatory Mechanism of the Bone Morphogenetic Protein (BMP) Signaling Pathway Involving the Carboxyl-Terminal Tail Domain of BMP Type II Receptor

por Chan, Mun Chun, Nguyen, Peter H., Davis, Brandi N., Ohoka, Nobumichi, Hayashi, Hidetoshi, Du, Keyong, Lagna, Giorgio, Hata, Akiko
Publicado em 2007

Down-regulation of Krüppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-β and Bone Mor...

por Davis-Dusenbery, Brandi N., Chan, Mun Chun, Reno, Kelsey E., Weisman, Alexandra S., Layne, Matthew D., Lagna, Giorgio, Hata, Akiko
Publicado em 2011

Bone Morphogenetic Protein Signaling in Vascular Disease: ANTI-INFLAMMATORY ACTION THROUGH MYOCARDIN-RELATED TRANSCRIPTION FACTOR A

por Wang, Dahai, Prakash, Jamunabai, Nguyen, Peter, Davis-Dusenbery, Brandi N., Hill, Nicholas S., Layne, Matthew D., Hata, Akiko, Lagna, Giorgio
Publicado em 2012

Bone morphogenetic protein signaling is required for RAD51-mediated maintenance of genome integrity in vascular endothelial cells

por Vattulainen-Collanus, Sanna, Southwood, Mark, Yang, Xu Dong, Moore, Stephen, Ghatpande, Prajakta, Morrell, Nicholas W., Lagna, Giorgio, Hata, Akiko
Publicado no Commun Biol (2018)

Hypoxia Potentiates MicroRNA-Mediated Gene Silencing through Posttranslational Modification of Argonaute2

por Wu, Connie, So, Jessica, Davis-Dusenbery, Brandi N., Qi, Hank H., Bloch, Donald B., Shi, Yang, Lagna, Giorgio, Hata, Akiko
Publicado em 2011

Bone Morphogenetic Protein 4 Promotes Vascular Smooth Muscle Contractility by Activating MicroRNA-21 (miR-21), which Down-regulates Expression of Family of Dedicator of Cytokinesis...

por Kang, Hara, Davis-Dusenbery, Brandi N., Nguyen, Peter H., Lal, Ashish, Lieberman, Judy, Van Aelst, Linda, Lagna, Giorgio, Hata, Akiko
Publicado em 2012

Hyperactive locomotion in a Drosophila model is a functional readout for the synaptic abnormalities underlying fragile X syndrome

por Kashima, Risa, Redmond, Patrick L., Ghatpande, Prajakta, Roy, Sougata, Kornberg, Thomas B., Hanke, Thomas, Knapp, Stefan, Lagna, Giorgio, Hata, Akiko
Publicado no Sci Signal (2017)

Molecular basis for antagonism between PDGF and the TGFβ family of signalling pathways by control of miR-24 expression

por Chan, Mun Chun, Hilyard, Aaron C, Wu, Connie, Davis, Brandi N, Hill, Nicholas S, Lal, Ashish, Lieberman, Judy, Lagna, Giorgio, Hata, Akiko
Publicado em 2010

The Amiloride Derivative Phenamil Attenuates Pulmonary Vascular Remodeling by Activating NFAT and the Bone Morphogenetic Protein Signaling Pathway

por Chan, Mun Chun, Weisman, Alexandra S., Kang, Hara, Nguyen, Peter H., Hickman, Tyler, Mecker, Samantha V., Hill, Nicholas S., Lagna, Giorgio, Hata, Akiko
Publicado em 2011

Acetylation of p53 stimulates miRNA processing and determines cell survival following genotoxic stress

por Chang, Jonathan, Davis-Dusenbery, Brandi N, Kashima, Risa, Jiang, Xuan, Marathe, Nisha, Sessa, Roberto, Louie, Justin, Gu, Wei, Lagna, Giorgio, Hata, Akiko
Publicado em 2013

Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice

por Jiang, Xuan, Hawkins, John S., Lee, Jerry, Lizama, Carlos O., Bos, Frank L., Zape, Joan P., Ghatpande, Prajakta, Peng, Yongbo, Louie, Justin, Lagna, Giorgio, Zovein, Ann C., Hata, Akiko
Publicado no Nat Commun (2017)

Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia

por Jiang, Xuan, Wooderchak-Donahue, Whitney L., McDonald, Jamie, Ghatpande, Prajakta, Baalbaki, Mai, Sandoval, Melissa, Hart, Daniel, Clay, Hilary, Coughlin, Shaun, Lagna, Giorgio, Bayrak-Toydemir, Pinar, Hata, Akiko
Publicado no Sci Signal (2018)