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Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha

The signal transducers of the Transforming Growth Factor β (TGFβ)/Bone Morphogenetic Protein (BMP), the Smads, promote the expression of a subset of miRNAs by facilitating the cleavage reaction by Drosha. The mechanism that limits Smad-mediated processing to a selective group of miRNAs remained hith...

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Detalhes bibliográficos
Main Authors: Davis, Brandi N., Hilyard, Aaron C., Nguyen, Peter H., Lagna, Giorgio, Hata, Akiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921543/
https://ncbi.nlm.nih.gov/pubmed/20705240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.07.011
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