Is MDMX the better target?

door Kon, Ning, Gu, Wei
Gepubliceerd in Aging (Albany NY) (2018)

p53 activation vs. stabilization: an acetylation tale from the C-terminal tail

door Kon, Ning, Gu, Wei
Gepubliceerd in Oncoscience (2021)

Acidic domains: “converse readers” for acetylation code

door Wang, Donglai, Kon, Ning, Gu, Wei
Gepubliceerd in Oncotarget (2016)

Loss of SET reveals both the p53-dependent and the p53-independent functions in vivo

door Kon, Ning, Wang, Donglai, Gu, Wei
Gepubliceerd in Cell Death Dis (2019)

The “readers” of unacetylated p53 represent a new class of acidic domain proteins

door Wang, Donglai, Kon, Ning, Tavana, Omid, Gu, Wei
Gepubliceerd in Nucleus (2017)

Gpr17 in AgRP Neurons Regulates Feeding and Sensitivity to Insulin and Leptin

door Ren, Hongxia, Cook, Joshua R., Kon, Ning, Accili, Domenico
Gepubliceerd in Diabetes (2015)

Inactivation of arf-bp1 Induces p53 Activation and Diabetic Phenotypes in Mice

door Kon, Ning, Zhong, Jiayun, Qiang, Li, Accili, Domenico, Gu, Wei
Gepubliceerd in 2012

Regulation of the Mts1-Mts2-Dependent ade6-M26 Meiotic Recombination Hot Spot and Developmental Decisions by the Spc1 Mitogen-Activated Protein Kinase of Fission Yeast

door Kon, Ning, Schroeder, Stephanie C., Krawchuk, Michelle D., Wahls, Wayne P.
Gepubliceerd in 1998

Glucagon-Like Peptide 1 Inhibits the Sirtuin Deacetylase SirT1 to Stimulate Pancreatic β-Cell Mass Expansion

door Bastien-Dionne, Pierre-Olivier, Valenti, Luca, Kon, Ning, Gu, Wei, Buteau, Jean
Gepubliceerd in 2011

Differential effects on ARF stability by normal vs. oncogenic levels of c-Myc expression

door Chen, Delin, Kon, Ning, Zhong, Jiayun, Zhang, Pingzhao, Yu, Long, Gu, Wei
Gepubliceerd in 2013

Inhibition of Mdmx (Mdm4) in vivo induces anti-obesity effects

door Kon, Ning, Wang, Donglai, Li, Tongyuan, Jiang, Le, Qiang, Li, Gu, Wei
Gepubliceerd in Oncotarget (2018)

Robust p53 stabilization is dispensable for its activation and tumor suppressor function

door Kon, Ning, Churchill, Michael, Li, Huan, Mukherjee, Siddhartha, Manfredi, James J., Gu, Wei
Gepubliceerd in Cancer Res (2020)

Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the M26 meiotic recombination hotspot in Schizosaccharomyces pombe

door Kon, Ning, Krawchuk, Michelle D., Warren, B. Greg, Smith, Gerald R., Wahls, Wayne P.
Gepubliceerd in 1997

mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression

door Kon, Ning, Ou, Yang, Wang, Shang-Jui, Li, Huan, Rustgi, Anil K., Gu, Wei
Gepubliceerd in Genes Dev (2021)

Corrigendum: mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression

door Kon, Ning, Ou, Yang, Wang, Shang-Jui, Li, Huan, Rustgi, Anil K., Gu, Wei
Gepubliceerd in Genes Dev (2021)

Tumor suppression in the absence of p53-mediated cell cycle arrest, apoptosis, and senescence

door Li, Tongyuan, Kon, Ning, Jiang, Le, Tan, Minjia, Ludwig, Thomas, Zhao, Yingming, Baer, Richard, Gu, Wei
Gepubliceerd in 2012

SirT1 gain-of-function increases energy efficiency and prevents diabetes in mice

door Banks, Alexander S., Kon, Ning, Knight, Colette, Matsumoto, Michihiro, Gutiérrez-Juárez, Roger, Rossetti, Luciano, Gu, Wei, Accili, Domenico
Gepubliceerd in 2008

Ferroptosis as a p53-mediated activity during tumour suppression

door Jiang, Le, Kon, Ning, Li, Tongyuan, Wang, Shang–Jui, Su, Tao, Hibshoosh, Hanina, Baer, Richard, Gu, Wei
Gepubliceerd in Nature (2015)

ALOX12 is required for p53-mediated tumor suppression through a distinct ferroptosis pathway

door Chu, Bo, Kon, Ning, Chen, Delin, Li, Tongyuan, Liu, Tong, Jiang, Le, Song, Shujuan, Tavana, Omid, Gu, Wei
Gepubliceerd in Nat Cell Biol (2019)

Hepatic SirT1-Dependent Gain-of-Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions

door Qiang, Li, Kon, Ning, Zhao, Wenhui, Jiang, Le, Knight, Colette M., Welch, Carrie, Pajvani, Utpal, Gu, Wei, Accili, Domenico
Gepubliceerd in Cell Rep (2015)