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Loss of SET reveals both the p53-dependent and the p53-independent functions in vivo

Our previous study showed that the oncoprotein SET acts as a new reader of unacetylated p53 for transcriptional repression. To further elucidate the physiological significance of SET in vivo, we generated set knockout mice. Set knockout mice died during embryonic development between day 11.5 and day...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Kon, Ning, Wang, Donglai, Gu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411979/
https://ncbi.nlm.nih.gov/pubmed/30858352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1484-6
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