Tumor immunology and cancer vaccines

door Khleif, Samir N.
Gepubliceerd in 2005

Therapeutic Vaccines for Gastrointestinal Cancers

door Rahma, Osama E., Khleif, Samir N.
Gepubliceerd in 2011

HPV as a Model for the Development of Prophylactic and Therapeutic Cancer Vaccines

door Samara, Raed N., Khleif, Samir N.
Gepubliceerd in Curr Mol Med (2009)

The FDA Guidance on therapeutic cancer vaccines: the need for revision to include preventive cancer vaccines or for a new guidance dedicated to them

door Finn, Olivera J., Khleif, Samir N., Herberman, Ronald B.
Gepubliceerd in Cancer Prev Res (Phila) (2015)

AKT inhibition mitigates terminal differentiation and preserves central memory phenotype of CD8 T cells

door Abu Eid, Rasha, Friedman, Kevin, Mkrtichyan, Mikayel, Khleif, Samir N
Gepubliceerd in J Immunother Cancer (2014)

Is the “3+3” dose escalation phase 1 clinical trial design suitable for therapeutic cancer vaccine development? A recommendation for alternative design

door Rahma, Osama E., Gammoh, Emily, Simon, Richard M., Khleif, Samir N.
Gepubliceerd in 2014

High-dose treatment with ADXS11-001, a listeria monocytogenes (Lm)-listeriolysin O (LLO) immunotherapy, in women with cervical cancer

door Ghamande, Sharad, Mauro, David, Price, Cheryl, Wheatley, Donna, Janik, John, Khleif, Samir N
Gepubliceerd in J Immunother Cancer (2015)

Episomal expression of truncated listeriolysin O in LmddA-LLO-E7 vaccine enhances antitumor efficacy by preferentially inducing expansions of CD4(+)FoxP3(−) and CD8(+) T cells

door Chen, Zhisong, Ozbun, Laurent, Chong, Namju, Wallecha, Anu, Berzofsky, Jay A., Khleif, Samir N.
Gepubliceerd in 2014

Functional redundancy of PI3K isoforms in conventional T cells provides a selective Treg-targeting strategy through inhibition of PI3K-delta isoform

door Ahmad, Shamim, Mkrtichyan, Mikayel, Eid, Rasha Abu, Shrimali, Rajeev, Doroodchi, Atbin, Khleif, Samir N
Gepubliceerd in J Immunother Cancer (2014)

Immuno-Oncology biomarkers 2010 and beyond: Perspectives from the iSBTc/SITC biomarker task force

door Balwit James M, Marincola Francesco M, Khleif Samir N, Disis Mary L, Butterfield Lisa H
Gepubliceerd in 2010-12-01

Incomplete penetrance of familial retinoblastoma linked to germ-line mutations that result in partial loss of RB function

door Otterson, Gregory A., Chen, Wei-dong, Coxon, Amy B., Khleif, Samir N., Kaye, Frederic J.
Gepubliceerd in 1997

Immuno-Oncology biomarkers 2010 and beyond: Perspectives from the iSBTc/SITC biomarker task force

door Butterfield, Lisa H, Disis, Mary L, Khleif, Samir N, Balwit, James M, Marincola, Francesco M
Gepubliceerd in 2010

Molecular Characterization of Antigen-Peptide Pulsed Dendritic Cells: Immature Dendritic Cells Develop a Distinct Molecular Profile when Pulsed with Antigen Peptide

door Yang, Amy X., Chong, Numju, Jiang, Yufei, Catalano, Jennifer, Puri, Raj K., Khleif, Samir N.
Gepubliceerd in 2014

Preamble to the 2015 SITC immunotherapy biomarkers taskforce

door Butterfield, Lisa H, Disis, Mary L, Fox, Bernard A, Khleif, Samir N, Marincola, Francesco M
Gepubliceerd in J Immunother Cancer (2015)

Anti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy

door Mkrtichyan, Mikayel, Chong, Namju, Abu Eid, Rasha, Wallecha, Anu, Singh, Reshma, Rothman, John, Khleif, Samir N
Gepubliceerd in 2013

Akt1 and -2 inhibition diminishes terminal differentiation and enhances central memory CD8(+) T-cell proliferation and survival

door Abu Eid, Rasha, Friedman, Kevin M, Mkrtichyan, Mikayel, Walens, Andrea, King, William, Janik, John, Khleif, Samir N
Gepubliceerd in Oncoimmunology (2015)

SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art

door Butterfield, Lisa H., Disis, Mary L., Fox, Bernard A., Kaufman, David R., Khleif, Samir N., Wang, Ena
Gepubliceerd in J Immunother Cancer (2018)

Focus on the target: the tumor microenvironment, Society for Immunotherapy of Cancer Annual Meeting Workshop, October 24th-25th 2012

door Sunay, Melek Erdinc, Marincola, Francesco, Khleif, Samir N, Silverstein, Samuel C, Fox, Bernard A, Galon, Jerome, Emens, Leisha A
Gepubliceerd in 2013

B7-DC-Ig enhances vaccine effect by a novel mechanism dependent on PD-1 expression level on T cell subsets

door Mkrtichyan, Mikayel, Najjar, Yana G., Raulfs, Estella C., Liu, Linda, Langerman, Solomon, Guittard, Geoffrey, Ozbun, Laurent, Khleif, Samir N.
Gepubliceerd in J Immunol (2012)

Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.

door Khleif, S N, DeGregori, J, Yee, C L, Otterson, G A, Kaye, F J, Nevins, J R, Howley, P M
Gepubliceerd in 1996