How to Develop Treatments for Biologically Heterogeneous “Diseases”

le Simon, Richard M
Foilsithe 2012

Optimally splitting cases for training and testing high dimensional classifiers

le Dobbin, Kevin K, Simon, Richard M
Foilsithe 2011

On the Design of Combination Cancer Therapy

le Doroshow, James H., Simon, Richard M.
Foilsithe in Cell (2017)

D3Oncoprint: Stand-Alone Software to Visualize and Dynamically Explore Annotated Genomic Mutation Files

le Palmisano, Alida, Zhao, Yingdong, Simon, Richard M.
Foilsithe in JCO Clin Cancer Inform (2018)

Use of Archived Specimens in Evaluation of Prognostic and Predictive Biomarkers

le Simon, Richard M., Paik, Soonmyung, Hayes, Daniel F.
Foilsithe 2009

Using cross-validation to evaluate predictive accuracy of survival risk classifiers based on high-dimensional data

le Simon, Richard M., Subramanian, Jyothi, Li, Ming-Chung, Menezes, Supriya
Foilsithe 2011

Is the “3+3” dose escalation phase 1 clinical trial design suitable for therapeutic cancer vaccine development? A recommendation for alternative design

le Rahma, Osama E., Gammoh, Emily, Simon, Richard M., Khleif, Samir N.
Foilsithe 2014

Identification of pharmacodynamic biomarkers and common molecular mechanisms of response to genotoxic agents in cancer cell lines

le Min, Dong-Joon, Zhao, Yingdong, Monks, Anne, Palmisano, Alida, Hose, Curtis, Teicher, Beverly A., Doroshow, James H., Simon, Richard M.
Foilsithe in Cancer Chemother Pharmacol (2019)

Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases

le Becker, Kevin G., Simon, Richard M., Bailey-Wilson, Joan E., Freidlin, Boris, Biddison, William E., McFarland, Henry F., Trent, Jeffrey M.
Foilsithe 1998

Prognostic Factors in Patients Undergoing Lymphadenectomy for Malignant Melanoma

le Cohen, Max H., Ketcham, Alfred S., Felix, Wdward L., Li, Shou-Hua, Tomaszewski, Maria-Magdalena, Costa, Jose, Rabson, Alan S., Simon, Richard M., Rosenberg, Stevan A.
Foilsithe 1977

Application of Molecular Profiling in Clinical Trials for Advanced Metastatic Cancers

le Kummar, Shivaani, Williams, P. Mickey, Lih, Chih-Jian, Polley, Eric C., Chen, Alice P., Rubinstein, Larry V., Zhao, Yingdong, Simon, Richard M., Conley, Barbara A., Doroshow, James H.
Foilsithe in J Natl Cancer Inst (2015)

Efficiency of Prostate Cancer Diagnosis by MR/Ultrasound Fusion-Guided Biopsy vs Standard Extended-Sextant Biopsy for MR-Visible Lesions

le Siddiqui, M. Minhaj, George, Arvin K., Rubin, Rachel, Rais-Bahrami, Soroush, Parnes, Howard L., Merino, Maria J., Simon, Richard M., Turkbey, Baris, Choyke, Peter L., Wood, Bradford J., Pinto, Peter A.
Foilsithe in J Natl Cancer Inst (2016)

GeneMed: An Informatics Hub for the Coordination of Next-Generation Sequencing Studies that Support Precision Oncology Clinical Trials

le Zhao, Yingdong, Polley, Eric C, Li, Ming-Chung, Lih, Chih-Jian, Palmisano, Alida, Sims, David J, Rubinstein, Lawrence V, Conley, Barbara A, Chen, Alice P, Williams, P Mickey, Kummar, Shivaani, Doroshow, James H, Simon, Richard M
Foilsithe in Cancer Inform (2015)

The Exomes of the NCI-60 Panel: a Genomic Resource for Cancer Biology and Systems Pharmacology

le Abaan, Ogan D., Polley, Eric C., Davis, Sean R., Zhu, Yuelin J., Bilke, Sven, Walker, Robert L., Pineda, Marbin, Gindin, Yevgeniy, Jiang, Yuan, Reinhold, William C., Holbeck, Susan L., Simon, Richard M., Doroshow, James H., Pommier, Yves, Meltzer, Paul S.
Foilsithe in Cancer Res (2013)

Comparison of MR/Ultrasound Fusion–Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer

le Siddiqui, M. Minhaj, Rais-Bahrami, Soroush, Turkbey, Baris, George, Arvin K., Rothwax, Jason, Shakir, Nabeel, Okoro, Chinonyerem, Raskolnikov, Dima, Parnes, Howard L., Linehan, W. Marston, Merino, Maria J., Simon, Richard M., Choyke, Peter L., Wood, Bradford J., Pinto, Peter A.
Foilsithe in JAMA (2015)

Diagnostic value of biparametric magnetic resonance imaging (MRI) as an adjunct to prostate-specific antigen (PSA)-based detection of prostate cancer in men without prior biopsies

le Rais-Bahrami, Soroush, Siddiqui, M. Minhaj, Vourganti, Srinivas, Turkbey, Baris, Rastinehad, Ardeshir R., Stamatakis, Lambros, Truong, Hong, Walton-Diaz, Annerleim, Hoang, Anthony N., Nix, Jeffrey W., Merino, Maria J., Wood, Bradford J., Simon, Richard M., Choyke, Peter L., Pinto, Peter A.
Foilsithe in BJU Int (2014)

Accuracy of Multiparametric Magnetic Resonance Imaging in Confirming Eligibility for Active Surveillance for Men with Prostate Cancer

le Stamatakis, Lambros, Siddiqui, M. Minhaj, Nix, Jeffrey W., Logan, Jennifer, Rais-Bahrami, Soroush, Walton-Diaz, Annerleim, Hoang, Anthony N., Vourganti, Srinivas, Truong, Hong, Shuch, Brian, Parnes, Howard L., Turkbey, Baris, Choyke, Peter L., Wood, Bradford J., Simon, Richard M., Pinto, Peter A.
Foilsithe in Cancer (2013)

Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration

le McShane, Lisa M, Cavenagh, Margaret M, Lively, Tracy G, Eberhard, David A, Bigbee, William L, Williams, P Mickey, Mesirov, Jill P, Polley, Mei-Yin C, Kim, Kelly Y, Tricoli, James V, Taylor, Jeremy MG, Shuman, Deborah J, Simon, Richard M, Doroshow, James H, Conley, Barbara A
Foilsithe 2013

Criteria for the use of omics-based predictors in clinical trials

le McShane, Lisa M., Cavenagh, Margaret M., Lively, Tracy G., Eberhard, David A., Bigbee, William L., Williams, P. Mickey, Mesirov, Jill P., Polley, Mei-Yin C., Kim, Kelly Y., Tricoli, James V., Taylor, Jeremy M. G., Shuman, Deborah J., Simon, Richard M., Doroshow, James H., Conley, Barbara A.
Foilsithe 2013

Analytical Validation and Application of a Targeted Next-Generation Sequencing Mutation-Detection Assay for Use in Treatment Assignment in the NCI-MPACT Trial

le Lih, Chih-Jian, Sims, David J., Harrington, Robin D., Polley, Eric C., Zhao, Yingdong, Mehaffey, Michele G., Forbes, Thomas D., Das, Biswajit, Walsh, William D., Datta, Vivekananda, Harper, Kneshay N., Bouk, Courtney H., Rubinstein, Lawrence V., Simon, Richard M., Conley, Barbara A., Chen, Alice P., Kummar, Shivaani, Doroshow, James H., Williams, Paul M.
Foilsithe in J Mol Diagn (2016)