How to Develop Treatments for Biologically Heterogeneous “Diseases”

Por Simon, Richard M
Publicado em 2012

Optimally splitting cases for training and testing high dimensional classifiers

Por Dobbin, Kevin K, Simon, Richard M
Publicado em 2011

On the Design of Combination Cancer Therapy

Por Doroshow, James H., Simon, Richard M.
Publicado no Cell (2017)

D3Oncoprint: Stand-Alone Software to Visualize and Dynamically Explore Annotated Genomic Mutation Files

Por Palmisano, Alida, Zhao, Yingdong, Simon, Richard M.
Publicado no JCO Clin Cancer Inform (2018)

Use of Archived Specimens in Evaluation of Prognostic and Predictive Biomarkers

Por Simon, Richard M., Paik, Soonmyung, Hayes, Daniel F.
Publicado em 2009

Using cross-validation to evaluate predictive accuracy of survival risk classifiers based on high-dimensional data

Por Simon, Richard M., Subramanian, Jyothi, Li, Ming-Chung, Menezes, Supriya
Publicado em 2011

Is the “3+3” dose escalation phase 1 clinical trial design suitable for therapeutic cancer vaccine development? A recommendation for alternative design

Por Rahma, Osama E., Gammoh, Emily, Simon, Richard M., Khleif, Samir N.
Publicado em 2014

Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases

Por Becker, Kevin G., Simon, Richard M., Bailey-Wilson, Joan E., Freidlin, Boris, Biddison, William E., McFarland, Henry F., Trent, Jeffrey M.
Publicado em 1998

Prognostic Factors in Patients Undergoing Lymphadenectomy for Malignant Melanoma

Por Cohen, Max H., Ketcham, Alfred S., Felix, Wdward L., Li, Shou-Hua, Tomaszewski, Maria-Magdalena, Costa, Jose, Rabson, Alan S., Simon, Richard M., Rosenberg, Stevan A.
Publicado em 1977

Application of Molecular Profiling in Clinical Trials for Advanced Metastatic Cancers

Por Kummar, Shivaani, Williams, P. Mickey, Lih, Chih-Jian, Polley, Eric C., Chen, Alice P., Rubinstein, Larry V., Zhao, Yingdong, Simon, Richard M., Conley, Barbara A., Doroshow, James H.
Publicado no J Natl Cancer Inst (2015)

Efficiency of Prostate Cancer Diagnosis by MR/Ultrasound Fusion-Guided Biopsy vs Standard Extended-Sextant Biopsy for MR-Visible Lesions

Por Siddiqui, M. Minhaj, George, Arvin K., Rubin, Rachel, Rais-Bahrami, Soroush, Parnes, Howard L., Merino, Maria J., Simon, Richard M., Turkbey, Baris, Choyke, Peter L., Wood, Bradford J., Pinto, Peter A.
Publicado no J Natl Cancer Inst (2016)

GeneMed: An Informatics Hub for the Coordination of Next-Generation Sequencing Studies that Support Precision Oncology Clinical Trials

Por Zhao, Yingdong, Polley, Eric C, Li, Ming-Chung, Lih, Chih-Jian, Palmisano, Alida, Sims, David J, Rubinstein, Lawrence V, Conley, Barbara A, Chen, Alice P, Williams, P Mickey, Kummar, Shivaani, Doroshow, James H, Simon, Richard M
Publicado no Cancer Inform (2015)

The Exomes of the NCI-60 Panel: a Genomic Resource for Cancer Biology and Systems Pharmacology

Por Abaan, Ogan D., Polley, Eric C., Davis, Sean R., Zhu, Yuelin J., Bilke, Sven, Walker, Robert L., Pineda, Marbin, Gindin, Yevgeniy, Jiang, Yuan, Reinhold, William C., Holbeck, Susan L., Simon, Richard M., Doroshow, James H., Pommier, Yves, Meltzer, Paul S.
Publicado no Cancer Res (2013)

Comparison of MR/Ultrasound Fusion–Guided Biopsy With Ultrasound-Guided Biopsy for the Diagnosis of Prostate Cancer

Por Siddiqui, M. Minhaj, Rais-Bahrami, Soroush, Turkbey, Baris, George, Arvin K., Rothwax, Jason, Shakir, Nabeel, Okoro, Chinonyerem, Raskolnikov, Dima, Parnes, Howard L., Linehan, W. Marston, Merino, Maria J., Simon, Richard M., Choyke, Peter L., Wood, Bradford J., Pinto, Peter A.
Publicado no JAMA (2015)

Diagnostic value of biparametric magnetic resonance imaging (MRI) as an adjunct to prostate-specific antigen (PSA)-based detection of prostate cancer in men without prior biopsies

Por Rais-Bahrami, Soroush, Siddiqui, M. Minhaj, Vourganti, Srinivas, Turkbey, Baris, Rastinehad, Ardeshir R., Stamatakis, Lambros, Truong, Hong, Walton-Diaz, Annerleim, Hoang, Anthony N., Nix, Jeffrey W., Merino, Maria J., Wood, Bradford J., Simon, Richard M., Choyke, Peter L., Pinto, Peter A.
Publicado no BJU Int (2014)

Accuracy of Multiparametric Magnetic Resonance Imaging in Confirming Eligibility for Active Surveillance for Men with Prostate Cancer

Por Stamatakis, Lambros, Siddiqui, M. Minhaj, Nix, Jeffrey W., Logan, Jennifer, Rais-Bahrami, Soroush, Walton-Diaz, Annerleim, Hoang, Anthony N., Vourganti, Srinivas, Truong, Hong, Shuch, Brian, Parnes, Howard L., Turkbey, Baris, Choyke, Peter L., Wood, Bradford J., Simon, Richard M., Pinto, Peter A.
Publicado no Cancer (2013)

Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration

Por McShane, Lisa M, Cavenagh, Margaret M, Lively, Tracy G, Eberhard, David A, Bigbee, William L, Williams, P Mickey, Mesirov, Jill P, Polley, Mei-Yin C, Kim, Kelly Y, Tricoli, James V, Taylor, Jeremy MG, Shuman, Deborah J, Simon, Richard M, Doroshow, James H, Conley, Barbara A
Publicado em 2013

Criteria for the use of omics-based predictors in clinical trials

Por McShane, Lisa M., Cavenagh, Margaret M., Lively, Tracy G., Eberhard, David A., Bigbee, William L., Williams, P. Mickey, Mesirov, Jill P., Polley, Mei-Yin C., Kim, Kelly Y., Tricoli, James V., Taylor, Jeremy M. G., Shuman, Deborah J., Simon, Richard M., Doroshow, James H., Conley, Barbara A.
Publicado em 2013

Analytical Validation and Application of a Targeted Next-Generation Sequencing Mutation-Detection Assay for Use in Treatment Assignment in the NCI-MPACT Trial

Por Lih, Chih-Jian, Sims, David J., Harrington, Robin D., Polley, Eric C., Zhao, Yingdong, Mehaffey, Michele G., Forbes, Thomas D., Das, Biswajit, Walsh, William D., Datta, Vivekananda, Harper, Kneshay N., Bouk, Courtney H., Rubinstein, Lawrence V., Simon, Richard M., Conley, Barbara A., Chen, Alice P., Kummar, Shivaani, Doroshow, James H., Williams, Paul M.
Publicado no J Mol Diagn (2016)

Utility of Serial Multi-Parametric MRI in the Management of Prostate Cancer Patients on Active Surveillance

Por Walton Diaz, Annerleim, Shakir, Nabeel, George, Arvin K., Rais-Bahrami, Soroush, Turkbey, Baris, Rothwax, Jason T, Stamatakis, Lambros, Hong, Cheng William, Siddiqui, M. Minhaj, Okoro, Chinonyerem, Raskolnikov, Dima, Su, Daniel, Shih, Joanna, Han, Hui, Parnes, Howard L., Merino M, Maria J., Simon, Richard M, Wood, Bradford J., Choyke, Peter L., Pinto, Peter A.
Publicado no Urol Oncol (2015)