Chronic kidney disease with comorbid cardiac dysfunction exacerbates cardiac and renal damage

Autor Liu, Shan, Wang, Bing H., Kelly, Darren J., Krum, Henry, Kompa, Andrew R.
Vydáno v J Cell Mol Med (2017)

Contractile apparatus dysfunction early in the pathophysiology of diabetic cardiomyopathy

Autor Waddingham, Mark T, Edgley, Amanda J, Tsuchimochi, Hirotsugu, Kelly, Darren J, Shirai, Mikiyasu, Pearson, James T
Vydáno v World J Diabetes (2015)

Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat

Autor Leader, Catherine J., Kelly, Darren J., Sammut, Ivan A., Wilkins, Gerard T., Walker, Robert J.
Vydáno v Physiol Rep (2020)

Transcription Factors Krüppel-Like Factor 6 and Peroxisome Proliferator-Activated Receptor-γ Mediate High Glucose-Induced Thioredoxin-Interacting Protein

Autor Qi, Weier, Chen, Xinming, Holian, John, Tan, Christina Y.R., Kelly, Darren J., Pollock, Carol A.
Vydáno 2009

Role of Krüppel-like factor 6 in transforming growth factor-β1-induced epithelial-mesenchymal transition of proximal tubule cells

Autor Holian, John, Qi, Weier, Kelly, Darren J., Zhang, Yuan, Mreich, Ellein, Pollock, Carol A., Chen, Xin-Ming
Vydáno 2008

Role of the eNOS-NO System in Regulating the Antiproteinuric Effects of VEGF Receptor 2 Inhibition in Diabetes

Autor Advani, Andrew, Connelly, Kim A., Advani, Suzanne L., Thai, Kerri, Zhang, Yuan, Kelly, Darren J., Gilbert, Richard E.
Vydáno 2013

High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy

Autor Bugyei-Twum, Antoinette, Advani, Andrew, Advani, Suzanne L, Zhang, Yuan, Thai, Kerri, Kelly, Darren J, Connelly, Kim A
Vydáno 2014

High Glucose-Induced Thioredoxin-Interacting Protein in Renal Proximal Tubule Cells Is Independent of Transforming Growth Factor-β1

Autor Qi, Weier, Chen, Xinming, Gilbert, Richard E., Zhang, Yuan, Waltham, Mark, Schache, Maria, Kelly, Darren J., Pollock, Carol A.
Vydáno 2007

The Uremic Toxin Adsorbent AST-120 Abrogates Cardiorenal Injury Following Myocardial Infarction

Autor Lekawanvijit, Suree, Kumfu, Sirinart, Wang, Bing H., Manabe, Minako, Nishijima, Fuyuhiko, Kelly, Darren J., Krum, Henry, Kompa, Andrew R.
Vydáno 2013

FT011, a Novel Cardiorenal Protective Drug, Reduces Inflammation, Gliosis and Vascular Injury in Rats with Diabetic Retinopathy

Autor Deliyanti, Devy, Zhang, Yuan, Khong, Fay, Berka, David R., Stapleton, David I., Kelly, Darren J., Wilkinson-Berka, Jennifer L.
Vydáno v PLoS One (2015)

PKC-β1 Mediates Glucose-Induced Akt Activation and TGF-β1 Upregulation in Mesangial Cells

Autor Wu, Dongcheng, Peng, Fangfang, Zhang, Baifang, Ingram, Alistair J., Kelly, Darren J., Gilbert, Richard E., Gao, Bo, Krepinsky, Joan C.
Vydáno 2009

Chronic Kidney Disease-Induced Cardiac Fibrosis Is Ameliorated by Reducing Circulating Levels of a Non-Dialysable Uremic Toxin, Indoxyl Sulfate

Autor Lekawanvijit, Suree, Kompa, Andrew R., Manabe, Minako, Wang, Bing H., Langham, Robyn G., Nishijima, Fuyuhiko, Kelly, Darren J., Krum, Henry
Vydáno 2012

Contribution of microRNA to pathological fibrosis in cardio-renal syndrome: impact of uremic toxins

Autor Rana, Indrajeetsinh, Kompa, Andrew R, Skommer, Joanna, Wang, Bing H, Lekawanvijit, Suree, Kelly, Darren J, Krum, Henry, Charchar, Fadi J
Vydáno v Physiol Rep (2015)

Contribution of microRNA to pathological fibrosis in cardio-renal syndrome: impact of uremic toxins

Autor Rana, Indrajeetsinh, Kompa, Andrew R., Skommer, Joanna, Wang, Bing H., Lekawanvijit, Suree, Kelly, Darren J., Krum, Henry, Charchar, Fadi J.
Vydáno v Physiol Rep (2015)

Pathological Expression of Renin and Angiotensin II in the Renal Tubule after Subtotal Nephrectomy : Implications for the Pathogenesis of Tubulointerstitial Fibrosis

Autor Gilbert, Richard E., Wu, Leonard L., Kelly, Darren J., Cox, Alison, Wilkinson-Berka, Jennifer L., Johnston, Colin I., Cooper, Mark E.
Vydáno 1999

3′,4′-Dihydroxyflavonol Antioxidant Attenuates Diastolic Dysfunction and Cardiac Remodeling in Streptozotocin-Induced Diabetic m(Ren2)27 Rats

Autor Khong, Fay Lin, Zhang, Yuan, Edgley, Amanda J., Qi, Weier, Connelly, Kim A., Woodman, Owen L., Krum, Henry, Kelly, Darren J.
Vydáno 2011

Inhibition of Platelet-Derived Growth Factor Promotes Pericyte Loss and Angiogenesis in Ischemic Retinopathy

Autor Wilkinson-Berka, Jennifer L., Babic, Sanja, de Gooyer, Tanyth, Stitt, Alan W., Jaworski, Kassie, Ong, Leslie G. T., Kelly, Darren J., Gilbert, Richard E.
Vydáno 2004

Obesity Is Associated with Lower Coronary Microvascular Density

Autor Campbell, Duncan J., Somaratne, Jithendra B., Prior, David L., Yii, Michael, Kenny, James F., Newcomb, Andrew E., Kelly, Darren J., Black, Mary Jane
Vydáno 2013

The Renin-Angiotensin System Influences Ocular Endothelial Cell Proliferation in Diabetes : Transgenic and Interventional Studies

Autor Moravski, Christina J., Skinner, Sandford L., Stubbs, Anthony J., Sarlos, Stella, Kelly, Darren J., Cooper, Mark E., Gilbert, Richard E., Wilkinson-Berka, Jennifer L.
Vydáno 2003

A Purpose-Synthesised Anti-Fibrotic Agent Attenuates Experimental Kidney Diseases in the Rat

Autor Gilbert, Richard E., Zhang, Yuan, Williams, Spencer J., Zammit, Steven C., Stapleton, David I., Cox, Alison J., Krum, Henry, Langham, Robyn, Kelly, Darren J.
Vydáno 2012