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Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat

Hypertension plays an important role in the development and progression of chronic kidney disease. Studies to date, with mineralocorticoid receptor antagonists (MRA), have demonstrated varying degrees of results in modifying the development of renal fibrosis. This study aimed to investigate whether...

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Publicado en:Physiol Rep
Autores principales: Leader, Catherine J., Kelly, Darren J., Sammut, Ivan A., Wilkins, Gerard T., Walker, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243196/
https://ncbi.nlm.nih.gov/pubmed/32441493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14448
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