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Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat

Hypertension plays an important role in the development and progression of chronic kidney disease. Studies to date, with mineralocorticoid receptor antagonists (MRA), have demonstrated varying degrees of results in modifying the development of renal fibrosis. This study aimed to investigate whether...

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Библиографические подробности
Опубликовано в: :Physiol Rep
Главные авторы: Leader, Catherine J., Kelly, Darren J., Sammut, Ivan A., Wilkins, Gerard T., Walker, Robert J.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243196/
https://ncbi.nlm.nih.gov/pubmed/32441493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14448
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