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Spironolactone mitigates, but does not reverse, the progression of renal fibrosis in a transgenic hypertensive rat

Hypertension plays an important role in the development and progression of chronic kidney disease. Studies to date, with mineralocorticoid receptor antagonists (MRA), have demonstrated varying degrees of results in modifying the development of renal fibrosis. This study aimed to investigate whether...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Leader, Catherine J., Kelly, Darren J., Sammut, Ivan A., Wilkins, Gerard T., Walker, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243196/
https://ncbi.nlm.nih.gov/pubmed/32441493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14448
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