Myocardial global longitudinal strain: An early indicator of cardiac interstitial fibrosis modified by spironolactone, in a unique hypertensive rat model

OBJECTIVES: Is global longitudinal strain (GLS) a more accurate non-invasive measure of histological myocardial fibrosis than left ventricular ejection fraction (LVEF) in a hypertensive rodent model. BACKGROUND: Hypertension results in left ventricular hypertrophy and cardiac dysfunction. Speckle-tr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Leader, Catherine J., Moharram, Mohammed, Coffey, Sean, Sammut, Ivan A., Wilkins, Gerard W., Walker, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690508/
https://ncbi.nlm.nih.gov/pubmed/31404095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220837
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