Cardiac Magnetic Resonance Assessment of Interstitial Myocardial Fibrosis and Cardiomyocyte Hypertrophy in Hypertensive Mice Treated With Spironolactone

BACKGROUND: Nearly 50% of patients with heart failure (HF) have preserved LV ejection fraction, with interstitial fibrosis and cardiomyocyte hypertrophy as early manifestations of pressure overload. However, methods to assess both tissue characteristics dynamically and noninvasively with therapy are...

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Bibliografske podrobnosti
izdano v:J Am Heart Assoc
Main Authors: Coelho‐Filho, Otavio R., Shah, Ravi V., Neilan, Tomas G., Mitchell, Richard, Moreno, Heitor, Kwong, Raymond, Jerosch‐Herold, Michael
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2014
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309062/
https://ncbi.nlm.nih.gov/pubmed/24965024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000790
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