Cardiac Magnetic Resonance Assessment of Interstitial Myocardial Fibrosis and Cardiomyocyte Hypertrophy in Hypertensive Mice Treated With Spironolactone

BACKGROUND: Nearly 50% of patients with heart failure (HF) have preserved LV ejection fraction, with interstitial fibrosis and cardiomyocyte hypertrophy as early manifestations of pressure overload. However, methods to assess both tissue characteristics dynamically and noninvasively with therapy are...

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Bibliografische gegevens
Gepubliceerd in:J Am Heart Assoc
Hoofdauteurs: Coelho‐Filho, Otavio R., Shah, Ravi V., Neilan, Tomas G., Mitchell, Richard, Moreno, Heitor, Kwong, Raymond, Jerosch‐Herold, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2014
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309062/
https://ncbi.nlm.nih.gov/pubmed/24965024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000790
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