Cardiac Magnetic Resonance Assessment of Interstitial Myocardial Fibrosis and Cardiomyocyte Hypertrophy in Hypertensive Mice Treated With Spironolactone

BACKGROUND: Nearly 50% of patients with heart failure (HF) have preserved LV ejection fraction, with interstitial fibrosis and cardiomyocyte hypertrophy as early manifestations of pressure overload. However, methods to assess both tissue characteristics dynamically and noninvasively with therapy are...

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Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Coelho‐Filho, Otavio R., Shah, Ravi V., Neilan, Tomas G., Mitchell, Richard, Moreno, Heitor, Kwong, Raymond, Jerosch‐Herold, Michael
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2014
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309062/
https://ncbi.nlm.nih.gov/pubmed/24965024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000790
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