Cardiac Magnetic Resonance Assessment of Interstitial Myocardial Fibrosis and Cardiomyocyte Hypertrophy in Hypertensive Mice Treated With Spironolactone

BACKGROUND: Nearly 50% of patients with heart failure (HF) have preserved LV ejection fraction, with interstitial fibrosis and cardiomyocyte hypertrophy as early manifestations of pressure overload. However, methods to assess both tissue characteristics dynamically and noninvasively with therapy are...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Coelho‐Filho, Otavio R., Shah, Ravi V., Neilan, Tomas G., Mitchell, Richard, Moreno, Heitor, Kwong, Raymond, Jerosch‐Herold, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309062/
https://ncbi.nlm.nih.gov/pubmed/24965024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.114.000790
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