A Purpose-Synthesised Anti-Fibrotic Agent Attenuates Experimental Kidney Diseases in the Rat

BACKGROUND AND PURPOSE: Locally-active growth factors have been implicated in the pathogenesis of many diseases in which organ fibrosis is a characteristic feature. In the setting of chronic kidney disease (CKD), two such pro-fibrotic factors, transforming growth factor-ß (TGF-ß) and platelet-derive...

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Detalhes bibliográficos
Main Authors: Gilbert, Richard E., Zhang, Yuan, Williams, Spencer J., Zammit, Steven C., Stapleton, David I., Cox, Alison J., Krum, Henry, Langham, Robyn, Kelly, Darren J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468513/
https://ncbi.nlm.nih.gov/pubmed/23071743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047160
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