Membrane protein secretases.

Por Hooper, N M, Karran, E H, Turner, A J
Publicado em 1997

In vivo model of cartilage degradation--effects of a matrix metalloproteinase inhibitor.

Por Karran, E H, Young, T J, Markwell, R E, Harper, G P
Publicado em 1995

Angiotensin-converting enzyme secretase is inhibited by zinc metalloprotease inhibitors and requires its substrate to be inserted in a lipid bilayer.

Por Parvathy, S, Oppong, S Y, Karran, E H, Buckle, D R, Turner, A J, Hooper, N M
Publicado em 1997

Chronic treatment with a novel γ-secretase modulator, JNJ-40418677, inhibits amyloid plaque formation in a mouse model of Alzheimer's disease

Por Van Broeck, B, Chen, J-M, Tréton, G, Desmidt, M, Hopf, C, Ramsden, N, Karran, E, Mercken, M, Rowley, A
Publicado em 2011

Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide.

Por Ward, R V, Jennings, K H, Jepras, R, Neville, W, Owen, D E, Hawkins, J, Christie, G, Davis, J B, George, A, Karran, E H, Howlett, D R
Publicado em 2000

Prdm6 Is Essential for Cardiovascular Development In Vivo

Por Gewies, Andreas, Castineiras-Vilarino, Mercedes, Ferch, Uta, Jährling, Nina, Heinrich, Katja, Hoeckendorf, Ulrike, Przemeck, Gerhard K. H., Munding, Matthias, Groß, Olaf, Schroeder, Timm, Horsch, Marion, Karran, E. Loraine, Majid, Aneela, Antonowicz, Stefan, Beckers, Johannes, Hrabé de Angelis, Martin, Dodt, Hans-Ulrich, Peschel, Christian, Förster, Irmgard, Dyer, Martin J. S., Ruland, Jürgen
Publicado em 2013

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

Por Chapuis, J, Hansmannel, F, Gistelinck, M, Mounier, A, Van Cauwenberghe, C, Kolen, K V, Geller, F, Sottejeau, Y, Harold, D, Dourlen, P, Grenier-Boley, B, Kamatani, Y, Delepine, B, Demiautte, F, Zelenika, D, Zommer, N, Hamdane, M, Bellenguez, C, Dartigues, J-F, Hauw, J-J, Letronne, F, Ayral, A-M, Sleegers, K, Schellens, A, Broeck, L V, Engelborghs, S, De Deyn, P P, Vandenberghe, R, O'Donovan, M, Owen, M, Epelbaum, J, Mercken, M, Karran, E, Bantscheff, M, Drewes, G, Joberty, G, Campion, D, Octave, J-N, Berr, C, Lathrop, M, Callaerts, P, Mann, D, Williams, J, Buée, L, Dewachter, I, Van Broeckhoven, C, Amouyel, P, Moechars, D, Dermaut, B, Lambert, J-C
Publicado em 2013