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In vivo model of cartilage degradation--effects of a matrix metalloproteinase inhibitor.

OBJECTIVES--To develop a model of cartilage degradation that (i) enables the testing of synthetic, small molecular weight matrix metalloproteinase (MMP) inhibitors as agents to prevent cartilage erosion, (ii) permits the direct assay of the principal constituents of the extracellular matrix (collage...

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Bibliografiske detaljer
Main Authors: Karran, E H, Young, T J, Markwell, R E, Harper, G P
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1009964/
https://ncbi.nlm.nih.gov/pubmed/7677443
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