Bile acid transporters in health and disease

Por Kosters, Astrid, Karpen, Saul J.
Publicado em 2008

The role of inflammation in cholestasis – clinical and basic aspects

Por Kosters, Astrid, Karpen, Saul J.
Publicado em 2010

NUCLEAR RECEPTORS, INFLAMMATION AND LIVER DISEASE: INSIGHTS FOR CHOLESTATIC AND FATTY LIVER DISEASES

Por Arrese, Marco, Karpen, Saul J.
Publicado em 2010

Inflammatory Mediators Increase SUMOylation of Retinoid X Receptor α in a c-Jun N-Terminal Kinase–Dependent Manner in Human Hepatocellular Carcinoma Cells

Por Schneider Aguirre, Rebecca, Karpen, Saul J.
Publicado em 2013

Bile Acids Reach Out to the Spinal Cord: New Insights to the Pathogenesis of Itch and Analgesia in Cholestatic Liver Disease

Por Dawson, Paul A., Karpen, Saul J.
Publicado em 2014

Not all (bile acids) who wander are lost: The 1(st) report of a patient with an isolated NTCP defect

Por Karpen, Saul J., Dawson, Paul A.
Publicado no Hepatology (2014)

Intestinal transport and metabolism of bile acids

Por Dawson, Paul A., Karpen, Saul J.
Publicado no J Lipid Res (2015)

Patients With Biliary Atresia Have Elevated Direct/Conjugated Bilirubin Levels Shortly After Birth

Por Harpavat, Sanjiv, Finegold, Milton J., Karpen, Saul J.
Publicado em 2011

Progressive Familial Intrahepatic Cholestasis Type 3 –Overlapping presentation with Wilson disease

Por Ramraj, Ramya, Finegold, Milton J, Karpen, Saul J.
Publicado em 2012

Endotoxin leads to rapid subcellular re-localization of hepatic RXRα: A novel mechanism for reduced hepatic gene expression in inflammation

Por Ghose, Romi, Zimmerman, Tracy L, Thevananther, Sundararajah, Karpen, Saul J
Publicado em 2004

Impaired bile acid handling and aggravated liver injury in mice expressing a hepatocyte-specific RXRα variant lacking the DNA-Binding Domain

Por Kosters, Astrid, Felix, Julio C., Desai, Moreshwar S., Karpen, Saul J.
Publicado em 2013

Gene-specific alterations of hepatic nuclear receptor regulated gene expression by ligand activation or hepatocyte-selective knockout inhibition of RXRα signaling during inflammati...

Por Kosters, Astrid, Tian, Feng, Wan, Yvonne Yu-Jie, Karpen, Saul J.
Publicado em 2011

Nuclear Receptors: Mediators And Modifiers Of Inflammation-Induced Cholestasis

Por Mulder, Jaap, Karpen, Saul J., Tietge, Uwe J.F., Kuipers, Folkert
Publicado em 2009

Redundant roles for cJun-N-terminal kinase 1 and 2 in interleukin-1β–mediated reduction and modification of murine hepatic nuclear retinoid X receptor α

Por Kosters, Astrid, White, Damara D., Sun, Hongdan, Thevananther, Sundararajah, Karpen, Saul J.
Publicado em 2009

Cardiac Structural and Functional Alterations in Infants and Children with Biliary Atresia, Listed for Liver Transplantation

Por Desai, Moreshwar S., Zainuer, Shabier, Kennedy, Curtis, Kearney, Debra, Goss, John, Karpen, Saul J.
Publicado em 2011

Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives

Por Arab, Juan P., Karpen, Saul J., Dawson, Paul A., Arrese, Marco, Trauner, Michael
Publicado no Hepatology (2016)

Failure of P-selectin blockade alone to protect the liver from ischemia-reperfusion injury in the isolated blood-perfused rat liver

Por Wyllie, Samuel, Barshes, Neal R, Gao, Feng-Qin, Karpen, Saul J, Goss, John A
Publicado em 2008

Inflammation-associated upregulation of the sulfated steroid transporter Slc10a6 in mouse liver and macrophage cell lines

Por Kosters, Astrid, Abebe, Demesew F., Felix, Julio C., Dawson, Paul A., Karpen, Saul J.
Publicado no Hepatol Res (2015)

Rosiglitazone attenuates suppression of RXRα-dependent gene expression in inflamed liver

Por Ghose, Romi, Mulder, Jaap, von Furstenberg, Richard J., Thevananther, Sundararajah, Kuipers, Folkert, Karpen, Saul J.
Publicado em 2006

Hypertrophic cardiomyopathy and dysregulation of cardiac energetics in a mouse model of biliary fibrosis

Por Desai, Moreshwar S., Shabier, Zainuer, Taylor, Michael, Lam, Fong, Thevananther, Sundararajah, Kosters, Astrid, Karpen, Saul J.
Publicado em 2010