Rosiglitazone attenuates suppression of RXRα-dependent gene expression in inflamed liver

Antzeko izenburuak

• Endotoxin leads to rapid subcellular re-localization of hepatic RXRα: A novel mechanism for reduced hepatic gene expression in inflammation
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• Redundant roles for cJun-N-terminal kinase 1 and 2 in interleukin-1β–mediated reduction and modification of murine hepatic nuclear retinoid X receptor α
  nork: Kosters, Astrid, et al.
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• Impaired bile acid handling and aggravated liver injury in mice expressing a hepatocyte-specific RXRα variant lacking the DNA-Binding Domain
  nork: Kosters, Astrid, et al.
  Argitaratua: (2013)
• Gene-specific alterations of hepatic nuclear receptor regulated gene expression by ligand activation or hepatocyte-selective knockout inhibition of RXRα signaling during inflammation
  nork: Kosters, Astrid, et al.
  Argitaratua: (2011)