Redundant roles for cJun-N-terminal kinase 1 and 2 in interleukin-1β–mediated reduction and modification of murine hepatic nuclear retinoid X receptor α

BACKGROUND/AIMS: Retinoid X receptor α (RXRα), the heterodimeric partner for multiple nuclear receptors (NRs), was shown to be an essential target for inflammation-induced cJun-N-terminal kinase (JNK) signaling in vitro. This study aimed to explore the role of hepatic JNK signaling and its effects o...

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Main Authors: Kosters, Astrid, White, Damara D., Sun, Hongdan, Thevananther, Sundararajah, Karpen, Saul J.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818213/
https://ncbi.nlm.nih.gov/pubmed/19767119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.06.029
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