Beyond the Paclitaxel and Vinca Alkaloids: Next Generation of Plant-Derived Microtubule-Targeting Agents with Potential Anticancer Activity

Por Zhang, Dangquan, Kanakkanthara, Arun
Publicado no Cancers (Basel) (2020)

Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes

Por van Ree, Janine H., Nam, Hyun-Ja, Jeganathan, Karthik B., Kanakkanthara, Arun, van Deursen, Jan M.
Publicado no Nat Cell Biol (2016)

ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer

Por Kanakkanthara, Arun, Huntoon, Catherine J., Hou, Xiaonan, Zhang, Minzhi, Heinzen, Ethan P., O’Brien, Daniel R., Oberg, Ann L., John Weroha, S., Kaufmann, Scott H., Karnitz, Larry M.
Publicado no Nat Commun (2019)

Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have βI-Tubulin Mutations and Altered Expression of βII- and βIII-Tubulin Isotypes

Por Kanakkanthara, Arun, Wilmes, Anja, O'Brate, Aurora, Escuin, Daniel, Chan, Ariane, Gjyrezi, Ada, Crawford, Janet, Rawson, Pisana, Kivell, Bronwyn, Northcote, Peter T., Hamel, Ernest, Giannakakou, Paraskevi, Miller, John H.
Publicado em 2011

BRCA1 Deficiency Upregulates NNMT Which Reprograms Metabolism and Sensitizes Ovarian Cancer Cells to Mitochondrial Metabolic Targeting Agents

Por Kanakkanthara, Arun, Kurmi, Kiran, Ekstrom, Thomas L., Hou, Xiaonan, Purfeerst, Emma R., Heinzen, Ethan P., Correia, Cristina, Huntoon, Catherine J., O’Brien, Daniel, Hendrickson, Andrea E. Wahner, Dowdy, Sean C., Li, Hu, Oberg, Ann L., Hitosugi, Taro, Kaufmann, Scott H., Weroha, S. John, Karnitz, Larry M.
Publicado no Cancer Res (2019)

Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin α,β-heterodimers and microtubules

Por Field, Jessica J., Pera, Benet, Calvo, Enrique, Canales, Angeles, Zurwerra, Didier, Trigili, Chiara, Rodríguez-Salarichs, Javier, Matesanz, Ruth, Kanakkanthara, Arun, Wakefield, St. John, Singh, A. Jonathan, Jiménez-Barbero, Jesús, Northcote, Peter, Miller, John H., López, Juan Antonio, Hamel, Ernest, Barasoain, Isabel, Altmann, Karl-Heinz, Díaz, José Fernando
Publicado em 2012

Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation

Por Kanakkanthara, Arun, Jeganathan, Karthik B., Limzerwala, Jazeel F., Baker, Darren J., Hamada, Masakazu, Nam, Hyun-Ja, van Deursen, Willemijn H., Hamada, Naomi, Naylor, Ryan M., Becker, Nicole A., Davies, Brian A., van Ree, Janine H., Mer, Georges, Shapiro, Virginia S., Maher, L. James, Katzmann, David J., van Deursen, Jan M.
Publicado no Science (2016)