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Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes
Phosphatase and tensin homologue (Pten) suppresses neoplastic growth by negatively regulating PI(3)K signalling through its phosphatase activity(1). To gain insight into the actions of non-catalytic Pten domains in normal physiological processes and tumorigenesis(2,3), we engineered mice lacking the...
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| Publicat a: | Nat Cell Biol |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5004208/ https://ncbi.nlm.nih.gov/pubmed/27240320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3369 |
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