Structural Origins of Oxacillinase Specificity in Class D β-Lactamases

Por June, Cynthia M., Vallier, Beth C., Bonomo, Robert A., Leonard, David A., Powers, Rachel A.
Publicado em 2014

Kinetic characterization of GES-22 β-lactamase harboring the M169L clinical mutation

Por SARAL, Aysegul, Leonard, David A., DUZGUN, Azer OZAD, CICEK, Aysegul COPUR, June, Cynthia M., SANDALLI, Cemal
Publicado no J Antibiot (Tokyo) (2016)

A FLUORESCENT CARBAPENEM FOR STRUCTURE FUNCTION STUDIES OF PENICILLIN-BINDING PROTEINS, B-LACTAMASES AND B-LACTAM SENSORS

Por June, Cynthia M., Vaughan, Robert M., Ulberg, Lucas S., Bonomo, Robert A., Witucki, Laurie A., Leonard, David A.
Publicado em 2014

Multiple substitutions lead to increased loop flexibility and expanded specificity in Acinetobacter baumannii carbapenemase OXA-239

Por Harper, Thomas M., June, Cynthia M., Taracila, Magdalena A., Bonomo, Robert A., Powers, Rachel A., Leonard, David A.
Publicado no Biochem J (2018)

Clinical Variants of the Native Class D β-Lactamase of Acinetobacter baumannii Pose an Emerging Threat through Increased Hydrolytic Activity against Carbapenems

Por Schroder, Emma C., Klamer, Zachary L., Saral, Aysegul, Sugg, Kyle A., June, Cynthia M., Wymore, Troy, Szarecka, Agnieszka, Leonard, David A.
Publicado no Antimicrob Agents Chemother (2016)

Structures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam

Por Kaitany, Kip-Chumba J., Klinger, Neil V., June, Cynthia M., Ramey, Maddison E., Bonomo, Robert A., Powers, Rachel A., Leonard, David A.
Publicado em 2013

The structure of a doripenem‐bound OXA‐51 class D β‐lactamase variant with enhanced carbapenemase activity

Por June, Cynthia M., Muckenthaler, Taylor J., Schroder, Emma C., Klamer, Zachary L., Wawrzak, Zdzislaw, Powers, Rachel A., Szarecka, Agnieszka, Leonard, David A.
Publicado no Protein Sci (2016)

THE STRUCTURAL BASIS OF ACTIVITY AGAINST AZTREONAM AND EXTENDED SPECTRUM CEPHALOSPORINS FOR TWO CARBAPENEM-HYDROLYZING CLASS D B-LACTAMASES FROM ACINETOBACTER BAUMANNII

Por Mitchell, Joshua M., Clasman, Jozlyn R., June, Cynthia M., Kaitany, Kip-Chumba J., LaFleur, James R., Taracila, Magdalena A., Klinger, Neil V., Bonomo, Robert A., Wymore, Troy, Szarecka, Agnieszka, Powers, Rachel A., Leonard, David A.
Publicado no Biochemistry (2015)