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Kinetic characterization of GES-22 β-lactamase harboring the M169L clinical mutation
The class A β-lactamase GES-22 has been identified in Acinetobacter baumannii isolates in Turkey, and subsequently shown to differ from GES-11 by a single substitution (M169L). Because M169 is part of the omega loop, a structure that is known to have major effects on substrate selectivity in class A...
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| Publicado no: | J Antibiot (Tokyo) |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5106332/ https://ncbi.nlm.nih.gov/pubmed/27168312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ja.2016.48 |
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