CB1 Antagonism Exerts Specific Molecular Effects on Visceral and Subcutaneous Fat and Reverses Liver Steatosis in Diet-Induced Obese Mice

Por Jourdan, Tony, Djaouti, Louiza, Demizieux, Laurent, Gresti, Joseph, Vergès, Bruno, Degrace, Pascal
Publicado em 2010

Hepatic CB(1) Receptors Mediate Diet-Induced Insulin Resistance by Increasing de novo Synthesis of Long Chain Ceramides

Por Cinar, Resat, Godlewski, Grzegorz, Liu, Jie, Tam, Joseph, Jourdan, Tony, Mukhopadhyay, Bani, Harvey-White, Judith, Kunos, George
Publicado em 2013

Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase

Por Liu, Jie, Cinar, Resat, Xiong, Keming, Godlewski, Grzegorz, Jourdan, Tony, Lin, Yuhong, Ntambi, James M., Kunos, George
Publicado em 2013

Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity

Por Tam, Joseph, Godlewski, Grzegorz, Earley, Brian J., Zhou, Liang, Jourdan, Tony, Szanda, Gergö, Cinar, Resat, Kunos, George
Publicado em 2013

Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy

Por Jourdan, Tony, Szanda, Gergő, Rosenberg, Avi Z., Tam, Joseph, Earley, Brian James, Godlewski, Grzegorz, Cinar, Resat, Liu, Ziyi, Liu, Jie, Ju, Cynthia, Pacher, Pál, Kunos, George
Publicado no Proc Natl Acad Sci U S A (2014)

Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue

Por Godlewski, Grzegorz, Jourdan, Tony, Szanda, Gergő, Tam, Joseph, Resat Cinar, Harvey-White, Judith, Liu, Jie, Mukhopadhyay, Bani, Pacher, Pál, Ming Mo, Fong, Osei-Hyiaman, Douglas, George Kunos
Publicado no Sci Rep (2015)

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

Por Jourdan, Tony, Godlewski, Grzegorz, Cinar, Resat, Bertola, Adeline, Szanda, Gergö, Liu, Jie, Tarn, Joseph, Han, Tiffany, Mukhopadhyay, Bani, Skarulis, Monica C, Ju, Cynthia, Aouadis, Myriam, Czech, Michael P, Kunos, George
Publicado em 2013

Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes

Por Jourdan, Tony, Szanda, Gergő, Cinar, Resat, Godlewski, Grzegorz, Holovac, David J., Park, Joshua K., Nicoloro, Sarah, Shen, Yuefei, Liu, Jie, Rosenberg, Avi Z., Liu, Ziyi, Czech, Michael P., Kunos, George
Publicado no Diabetes (2017)

Cannabinoid CB(1) receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis

Por Cinar, Resat, Gochuico, Bernadette R., Iyer, Malliga R., Jourdan, Tony, Yokoyama, Tadafumi, Park, Joshua K., Coffey, Nathan J., Pri-Chen, Hadass, Szanda, Gergő, Liu, Ziyi, Mackie, Ken, Gahl, William A., Kunos, George
Publicado no JCI Insight (2017)

Peripheral Cannabinoid-1 Receptor Inverse Agonism Reduces Obesity by Reversing Leptin Resistance

Por Tam, Joseph, Cinar, Resat, Liu, Jie, Godlewski, Grzegorz, Wesley, Daniel, Jourdan, Tony, Szanda, Gergö, Mukhopadhyay, Bani, Chedester, Lee, Liow, Jeih-San, Innis, Robert B., Cheng, Kejun, Rice, Kenner C., Deschamps, Jeffrey R., Chorvat, Robert J., McElroy, John F., Kunos, George
Publicado em 2012

Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis

Por Cinar, Resat, Iyer, Malliga R., Liu, Ziyi, Cao, Zongxian, Jourdan, Tony, Erdelyi, Katalin, Godlewski, Grzegorz, Szanda, Gergő, Liu, Jie, Park, Joshua K., Mukhopadhyay, Bani, Rosenberg, Avi Z., Liow, Jeih-San, Lorenz, Robin G., Pacher, Pal, Innis, Robert B., Kunos, George
Publicado no JCI Insight (2016)