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Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase
High-fat diet (HFD)–induced obesity and insulin resistance are associated with increased activity of the endocannabinoid/CB(1) receptor (CB(1)R) system that promotes the hepatic expression of lipogenic genes, including stearoyl-CoA desaturase-1 (SCD1). Mice deficient in CB(1)R or SCD1 remain lean an...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839776/ https://ncbi.nlm.nih.gov/pubmed/24191036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309469110 |
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