PDGF‐induced fibroblast growth requires monounsaturated fatty acid production by stearoyl‐CoA desaturase

Stearoyl‐coenzyme A desaturase (SCD) catalyzes the Δ9‐cis desaturation of saturated fatty acids (SFA) to generate monounsaturated fatty acids (MUFA). This enzyme is highly up‐regulated by platelet‐derived growth factor (PDGF) in human fibroblasts. Accordingly, the analysis of cellular fatty acids by...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FEBS Open Bio
Main Authors: Coomans de Brachène, Alexandra, Dif, Nicolas, de Rocca Serra, Audrey, Bonnineau, Chloé, Velghe, Amélie I., Larondelle, Yvan, Tyteca, Donatienne, Demoulin, Jean‐Baptiste
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337901/
https://ncbi.nlm.nih.gov/pubmed/28286737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12194
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