PDGF‐induced fibroblast growth requires monounsaturated fatty acid production by stearoyl‐CoA desaturase

Stearoyl‐coenzyme A desaturase (SCD) catalyzes the Δ9‐cis desaturation of saturated fatty acids (SFA) to generate monounsaturated fatty acids (MUFA). This enzyme is highly up‐regulated by platelet‐derived growth factor (PDGF) in human fibroblasts. Accordingly, the analysis of cellular fatty acids by...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Coomans de Brachène, Alexandra, Dif, Nicolas, de Rocca Serra, Audrey, Bonnineau, Chloé, Velghe, Amélie I., Larondelle, Yvan, Tyteca, Donatienne, Demoulin, Jean‐Baptiste
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337901/
https://ncbi.nlm.nih.gov/pubmed/28286737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12194
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