Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase

High-fat diet (HFD)–induced obesity and insulin resistance are associated with increased activity of the endocannabinoid/CB(1) receptor (CB(1)R) system that promotes the hepatic expression of lipogenic genes, including stearoyl-CoA desaturase-1 (SCD1). Mice deficient in CB(1)R or SCD1 remain lean an...

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Détails bibliographiques
Auteurs principaux: Liu, Jie, Cinar, Resat, Xiong, Keming, Godlewski, Grzegorz, Jourdan, Tony, Lin, Yuhong, Ntambi, James M., Kunos, George
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839776/
https://ncbi.nlm.nih.gov/pubmed/24191036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309469110
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