A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α

Por van der Wel, Tom, Janssen, Freek J., Baggelaar, Marc P., Deng, Hui, den Dulk, Hans, Overkleeft, Herman S., van der Stelt, Mario
Publicado no J Lipid Res (2015)

Comprehensive Analysis of Structure Activity Relationships of α-Ketoheterocycles as sn-1-Diacylglycerol Lipase α Inhibitors

Por Janssen, Freek J., Baggelaar, Marc P., Hummel, Jessica J. A., Overkleeft, Herman S., Cravatt, Benjamin F., Boger, Dale L., van der Stelt, Mario
Publicado no J Med Chem (2015)

A highly selective, reversible inhibitor identified by comparative chemoproteomics modulates diacylglycerol lipase activity in neurons

Por Baggelaar, Marc P., Chameau, Pascal J. P., Kantae, Vasudev, Hummel, Jessica, Hsu, Ku-Lung, Janssen, Freek, van der Wel, Tom, Soethoudt, Marjolein, Deng, Hui, den Dulk, Hans, Allarà, Marco, Florea, Bogdan I., Di Marzo, Vincenzo, Wadman, Wytse J., Kruse, Chris G., Overkleeft, Herman S., Hankemeier, Thomas, Werkman, Taco R., Cravatt, Benjamin F., van der Stelt, Mario
Publicado no J Am Chem Soc (2015)