Tubulin is a molecular target of the Wnt-activating chemical probe

af Fukuda, Yasunori, Sano, Osamu, Kazetani, Kenichi, Yamamoto, Koji, Iwata, Hidehisa, Matsui, Junji
Udgivet i BMC Biochem (2016)

Using a biologically annotated library to analyze the anticancer mechanism of serine palmitoyl transferase (SPT) inhibitors

af Sano, Osamu, Kazetani, Ken‐ichi, Adachi, Ryutaro, Kurasawa, Osamu, Kawamoto, Tomohiro, Iwata, Hidehisa
Udgivet i FEBS Open Bio (2017)

Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles

af Otake, Kentaro, Adachi‐Tominari, Keiko, Nagai, Hiroaki, Saito, Masayo, Sano, Osamu, Hirozane, Yoshihiko, Iwata, Hidehisa
Udgivet i FEBS Open Bio (2021)

A novel pyrrolo[3, 2‐d]pyrimidine derivative, as a vascular endothelial growth factor receptor and platelet‐derived growth factor receptor tyrosine kinase inhibitor, shows potent a...

af Awazu, Yoshiko, Mizutani, Akio, Nagase, Yoshinori, Iwata, Hidehisa, Oguro, Yuya, Miki, Hiroshi, Imamura, Shinichi, Hori, Akira
Udgivet i Cancer Sci (2012)

Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition

af Ono, Akito, Sano, Osamu, Kazetani, Ken-ichi, Muraki, Takamichi, Imamura, Keisuke, Sumi, Hiroyuki, Matsui, Junji, Iwata, Hidehisa
Udgivet i PLoS One (2017)

A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling

af Shiba-Fukushima, Kahori, Inoshita, Tsuyoshi, Sano, Osamu, Iwata, Hidehisa, Ishikawa, Kei-ichi, Okano, Hideyuki, Akamatsu, Wado, Imai, Yuzuru, Hattori, Nobutaka
Udgivet i iScience (2020)

Structure-Based Approach for the Discovery of Pyrrolo[3,2-d]pyrimidine-Based EGFR T790M/L858R Mutant Inhibitors

af Sogabe, Satoshi, Kawakita, Youichi, Igaki, Shigeru, Iwata, Hidehisa, Miki, Hiroshi, Cary, Douglas R., Takagi, Terufumi, Takagi, Shinji, Ohta, Yoshikazu, Ishikawa, Tomoyasu
Udgivet 2012

Synthetic mRNA‐based differentiation method enables early detection of Parkinson's phenotypes in neurons derived from Gaucher disease‐induced pluripotent stem cells

af Akiyama, Tomohiko, Sato, Saeko, Ko, Shigeru B. H., Sano, Osamu, Sato, Sho, Saito, Masayo, Nagai, Hiroaki, Ko, Minoru S. H., Iwata, Hidehisa
Udgivet i Stem Cells Transl Med (2020)

A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases

af Iwata, Hidehisa, Oki, Hideyuki, Okada, Kengo, Takagi, Terufumi, Tawada, Michiko, Miyazaki, Yasushi, Imamura, Shinichi, Hori, Akira, Lawson, J. David, Hixon, Mark S., Kimura, Hiroyuki, Miki, Hiroshi
Udgivet 2012

A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells

af Wakita, Masahiro, Takahashi, Akiko, Sano, Osamu, Loo, Tze Mun, Imai, Yoshinori, Narukawa, Megumi, Iwata, Hidehisa, Matsudaira, Tatsuyuki, Kawamoto, Shimpei, Ohtani, Naoko, Yoshimori, Tamotsu, Hara, Eiji
Udgivet i Nat Commun (2020)

Anti‐angiogenic and anti‐tumor effects of TAK‐593, a potent and selective inhibitor of vascular endothelial growth factor and platelet‐derived growth factor receptor tyrosine kinas...

af Awazu, Yoshiko, Mizutani, Akio, Nagase, Yoshinori, Tsuchiya, Shuntarou, Nakamura, Kazuhide, Kakoi, Yuichi, Kitahara, Osamu, Takeuchi, Toshiyuki, Yamasaki, Seiji, Miyamoto, Naoki, Iwata, Hidehisa, Miki, Hiroshi, Imamura, Shinichi, Hori, Akira
Udgivet i Cancer Sci (2013)