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Tubulin is a molecular target of the Wnt-activating chemical probe

BACKGROUND: In drug discovery research, cell-based phenotypic screening is an essential method for obtaining potential drug candidates. Revealing the mechanism of action is a key step on the path to drug discovery. However, elucidating the target molecules of hit compounds from phenotypic screening...

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Podrobná bibliografie
Vydáno v:BMC Biochem
Hlavní autoři: Fukuda, Yasunori, Sano, Osamu, Kazetani, Kenichi, Yamamoto, Koji, Iwata, Hidehisa, Matsui, Junji
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873989/
https://ncbi.nlm.nih.gov/pubmed/27207629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12858-016-0066-9
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