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A novel pyrrolo[3, 2‐d]pyrimidine derivative, as a vascular endothelial growth factor receptor and platelet‐derived growth factor receptor tyrosine kinase inhibitor, shows potent antitumor activity by suppression of tumor angiogenesis
We recently reported that compound 20d (comp.20d), a novel pyrrolo[3, 2‐d]pyrimidine derivative, is a potent and selective inhibitor of tumor angiogenesis‐related kinases, including vascular endothelial growth factor receptor (VEGFR) and platelet‐derived growth factor receptor (PDGFR). In this study...
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Опубликовано в: : | Cancer Sci |
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Главные авторы: | , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
John Wiley and Sons Inc.
2012
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7659339/ https://ncbi.nlm.nih.gov/pubmed/22320850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02238.x |
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