Tubulin is a molecular target of the Wnt-activating chemical probe

Autor Fukuda, Yasunori, Sano, Osamu, Kazetani, Kenichi, Yamamoto, Koji, Iwata, Hidehisa, Matsui, Junji
Vydáno v BMC Biochem (2016)

Using a biologically annotated library to analyze the anticancer mechanism of serine palmitoyl transferase (SPT) inhibitors

Autor Sano, Osamu, Kazetani, Ken‐ichi, Adachi, Ryutaro, Kurasawa, Osamu, Kawamoto, Tomohiro, Iwata, Hidehisa
Vydáno v FEBS Open Bio (2017)

Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles

Autor Otake, Kentaro, Adachi‐Tominari, Keiko, Nagai, Hiroaki, Saito, Masayo, Sano, Osamu, Hirozane, Yoshihiko, Iwata, Hidehisa
Vydáno v FEBS Open Bio (2021)

A novel pyrrolo[3, 2‐d]pyrimidine derivative, as a vascular endothelial growth factor receptor and platelet‐derived growth factor receptor tyrosine kinase inhibitor, shows potent a...

Autor Awazu, Yoshiko, Mizutani, Akio, Nagase, Yoshinori, Iwata, Hidehisa, Oguro, Yuya, Miki, Hiroshi, Imamura, Shinichi, Hori, Akira
Vydáno v Cancer Sci (2012)

Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition

Autor Ono, Akito, Sano, Osamu, Kazetani, Ken-ichi, Muraki, Takamichi, Imamura, Keisuke, Sumi, Hiroyuki, Matsui, Junji, Iwata, Hidehisa
Vydáno v PLoS One (2017)

A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling

Autor Shiba-Fukushima, Kahori, Inoshita, Tsuyoshi, Sano, Osamu, Iwata, Hidehisa, Ishikawa, Kei-ichi, Okano, Hideyuki, Akamatsu, Wado, Imai, Yuzuru, Hattori, Nobutaka
Vydáno v iScience (2020)

Structure-Based Approach for the Discovery of Pyrrolo[3,2-d]pyrimidine-Based EGFR T790M/L858R Mutant Inhibitors

Autor Sogabe, Satoshi, Kawakita, Youichi, Igaki, Shigeru, Iwata, Hidehisa, Miki, Hiroshi, Cary, Douglas R., Takagi, Terufumi, Takagi, Shinji, Ohta, Yoshikazu, Ishikawa, Tomoyasu
Vydáno 2012

Synthetic mRNA‐based differentiation method enables early detection of Parkinson's phenotypes in neurons derived from Gaucher disease‐induced pluripotent stem cells

Autor Akiyama, Tomohiko, Sato, Saeko, Ko, Shigeru B. H., Sano, Osamu, Sato, Sho, Saito, Masayo, Nagai, Hiroaki, Ko, Minoru S. H., Iwata, Hidehisa
Vydáno v Stem Cells Transl Med (2020)

A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases

Autor Iwata, Hidehisa, Oki, Hideyuki, Okada, Kengo, Takagi, Terufumi, Tawada, Michiko, Miyazaki, Yasushi, Imamura, Shinichi, Hori, Akira, Lawson, J. David, Hixon, Mark S., Kimura, Hiroyuki, Miki, Hiroshi
Vydáno 2012

A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells

Autor Wakita, Masahiro, Takahashi, Akiko, Sano, Osamu, Loo, Tze Mun, Imai, Yoshinori, Narukawa, Megumi, Iwata, Hidehisa, Matsudaira, Tatsuyuki, Kawamoto, Shimpei, Ohtani, Naoko, Yoshimori, Tamotsu, Hara, Eiji
Vydáno v Nat Commun (2020)

Anti‐angiogenic and anti‐tumor effects of TAK‐593, a potent and selective inhibitor of vascular endothelial growth factor and platelet‐derived growth factor receptor tyrosine kinas...

Autor Awazu, Yoshiko, Mizutani, Akio, Nagase, Yoshinori, Tsuchiya, Shuntarou, Nakamura, Kazuhide, Kakoi, Yuichi, Kitahara, Osamu, Takeuchi, Toshiyuki, Yamasaki, Seiji, Miyamoto, Naoki, Iwata, Hidehisa, Miki, Hiroshi, Imamura, Shinichi, Hori, Akira
Vydáno v Cancer Sci (2013)