Tubulin is a molecular target of the Wnt-activating chemical probe

per Fukuda, Yasunori, Sano, Osamu, Kazetani, Kenichi, Yamamoto, Koji, Iwata, Hidehisa, Matsui, Junji
Publicat a BMC Biochem (2016)

Using a biologically annotated library to analyze the anticancer mechanism of serine palmitoyl transferase (SPT) inhibitors

per Sano, Osamu, Kazetani, Ken‐ichi, Adachi, Ryutaro, Kurasawa, Osamu, Kawamoto, Tomohiro, Iwata, Hidehisa
Publicat a FEBS Open Bio (2017)

Quantitative comparison of the mRNA content of human iPSC‐derived motor neurons and their extracellular vesicles

per Otake, Kentaro, Adachi‐Tominari, Keiko, Nagai, Hiroaki, Saito, Masayo, Sano, Osamu, Hirozane, Yoshihiko, Iwata, Hidehisa
Publicat a FEBS Open Bio (2021)

A novel pyrrolo[3, 2‐d]pyrimidine derivative, as a vascular endothelial growth factor receptor and platelet‐derived growth factor receptor tyrosine kinase inhibitor, shows potent a...

per Awazu, Yoshiko, Mizutani, Akio, Nagase, Yoshinori, Iwata, Hidehisa, Oguro, Yuya, Miki, Hiroshi, Imamura, Shinichi, Hori, Akira
Publicat a Cancer Sci (2012)

Feedback activation of AMPK-mediated autophagy acceleration is a key resistance mechanism against SCD1 inhibitor-induced cell growth inhibition

per Ono, Akito, Sano, Osamu, Kazetani, Ken-ichi, Muraki, Takamichi, Imamura, Keisuke, Sumi, Hiroyuki, Matsui, Junji, Iwata, Hidehisa
Publicat a PLoS One (2017)

A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling

per Shiba-Fukushima, Kahori, Inoshita, Tsuyoshi, Sano, Osamu, Iwata, Hidehisa, Ishikawa, Kei-ichi, Okano, Hideyuki, Akamatsu, Wado, Imai, Yuzuru, Hattori, Nobutaka
Publicat a iScience (2020)

Structure-Based Approach for the Discovery of Pyrrolo[3,2-d]pyrimidine-Based EGFR T790M/L858R Mutant Inhibitors

per Sogabe, Satoshi, Kawakita, Youichi, Igaki, Shigeru, Iwata, Hidehisa, Miki, Hiroshi, Cary, Douglas R., Takagi, Terufumi, Takagi, Shinji, Ohta, Yoshikazu, Ishikawa, Tomoyasu
Publicat 2012

Synthetic mRNA‐based differentiation method enables early detection of Parkinson's phenotypes in neurons derived from Gaucher disease‐induced pluripotent stem cells

per Akiyama, Tomohiko, Sato, Saeko, Ko, Shigeru B. H., Sano, Osamu, Sato, Sho, Saito, Masayo, Nagai, Hiroaki, Ko, Minoru S. H., Iwata, Hidehisa
Publicat a Stem Cells Transl Med (2020)

A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases

per Iwata, Hidehisa, Oki, Hideyuki, Okada, Kengo, Takagi, Terufumi, Tawada, Michiko, Miyazaki, Yasushi, Imamura, Shinichi, Hori, Akira, Lawson, J. David, Hixon, Mark S., Kimura, Hiroyuki, Miki, Hiroshi
Publicat 2012

A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells

per Wakita, Masahiro, Takahashi, Akiko, Sano, Osamu, Loo, Tze Mun, Imai, Yoshinori, Narukawa, Megumi, Iwata, Hidehisa, Matsudaira, Tatsuyuki, Kawamoto, Shimpei, Ohtani, Naoko, Yoshimori, Tamotsu, Hara, Eiji
Publicat a Nat Commun (2020)

Anti‐angiogenic and anti‐tumor effects of TAK‐593, a potent and selective inhibitor of vascular endothelial growth factor and platelet‐derived growth factor receptor tyrosine kinas...

per Awazu, Yoshiko, Mizutani, Akio, Nagase, Yoshinori, Tsuchiya, Shuntarou, Nakamura, Kazuhide, Kakoi, Yuichi, Kitahara, Osamu, Takeuchi, Toshiyuki, Yamasaki, Seiji, Miyamoto, Naoki, Iwata, Hidehisa, Miki, Hiroshi, Imamura, Shinichi, Hori, Akira
Publicat a Cancer Sci (2013)