ET-23 THERAPEUTIC EFFICACY OF RETROVIRAL REPLICATING VECTORS IN HUMAN BREAST CANCER CNS METASTASIS MODEL

af Inagaki, Akihito, Hiraoka, Kei, Kamijima, Shuichi, Robbins, Joan, Jolly, Douglas, Gruber, Harry, Kasahara, Noriyuki
Udgivet 2014

ET-13 RETROVIRAL REPLICATING VECTOR (RRV)-MEDIATED PRODRUG ACTIVATOR GENE THERAPY WITH CODON-OPTIMIZED NITROREDUCTASE IN EXPERIMENTAL GLIOMA

af Collins, Sara, Logg, Christopher, Inagaki, Akihito, Kamijima, Shuichi, Lehouritis, Panos, Searle, Peter, Tangney, Mark, Kasahara, Noriyuki
Udgivet 2014

Differential Targeting of Stem Cells and Differentiated Glioblastomas by NK Cells

af Tseng, Han-Ching, Inagaki, Akihito, Bui, Vickie T., Cacalano, Nicholas, Kasahara, Noriyuki, Man, Yan-gao, Jewett, Anahid
Udgivet i J Cancer (2015)

EXTH-44. DEVELOPMENT OF RETROVIRAL REPLICATING VECTORS ENCODING SEQUENCE-OPTIMIZED NITROREDUCTASE FOR PRODRUG ACTIVATOR GENE THERAPY IN HUMAN GLIOMA MODELS

af Collins, Sara, Inagaki, Akihito, Tai, Chien-Kuo, Logg, Christopher R, Searle, Peter, Tangney, Mark, Kasahara, Noriyuki
Udgivet i Neuro Oncol (2020)

Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural...

af Kozlowska, Anna K., Tseng, Han-Ching, Kaur, Kawaljit, Topchyan, Paytsar, Inagaki, Akihito, Bui, Vickie T., Kasahara, Noriyuki, Cacalano, Nicholas, Jewett, Anahid
Udgivet i Cancer Immunol Immunother (2016)

THER-06. THERAPEUTIC EFFICACY OF RRV-MEDIATED PRODRUG ACTIVATOR GENE THERAPY IN CLINICAL TRIALS OF RECURRENT HIGH-GRADE GLIOMA AND IN MURINE ORTHOTOPIC MODELS OF INTRACEREBRAL GLIO...

af Richardson, Angela, Collins, Sara, Inagaki, Akihito, Armstrong, Valerie, Robbins, David, Ayad, Nagi, Gruber, Harry, Jolly, Douglas, Cloughesy, Timothy, Kasahara, Noriyuki
Udgivet i Neuro Oncol (2020)

PDTM-19. TOCA 511 & TOCA FC: PRE-CLINICAL PROOF OF CONCEPT IN MEDULLOBLASTOMA

af Richardson, Angela M, Collins, Sara A, Inagaki, Akihito, Armstrong, Valerie L, Roussel, Martine, Jolly, Douglas, Robbins, David J, Ayad, Nagi, Kasahara, Noriyuki
Udgivet i Neuro Oncol (2017)

Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model

af Mitchell, Leah A., Lopez Espinoza, Fernando, Mendoza, Daniel, Kato, Yuki, Inagaki, Akihito, Hiraoka, Kei, Kasahara, Noriyuki, Gruber, Harry E., Jolly, Douglas J., Robbins, Joan M.
Udgivet i Neuro Oncol (2017)

TMOD-15. TOCA 511 & TOCA FC: PRE-CLINICAL PROOF OF CONCEPT IN CNS METASTATIC BREAST CANCER

af Inagaki, Akihito, Richardson, Angela M, Collins, Sara A, Hiraoka, Kei, Kamijima, Shuichi, Shorr, Jolene, Gruber, Harry, Jolly, Douglas, Merchan, Jaime, Slingerland, Joyce M, Kasahara, Noriyuki
Udgivet i Neuro Oncol (2017)

STEM-24. THERAPEUTIC APPROACH OF STEM CELL CARRYING RETROVIRAL REPLICATING VECTORS IN HUMAN GLIOMA MODEL

af Inagaki, Akihito, Takahashi, Masamichi, Kamijima, Shuichi, Hiraoka, Kei, Tam, Quincy, Faure-Kumar, Emmanuelle, Treger, Janet, Bogan, Brooke, Hacke, Katrin, Collins, Sara, Jolly, Douglas, Kasahara, Noriyuki
Udgivet i Neuro Oncol (2019)

Radio-sensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector

af Takahashi, Masamichi, Valdes, Gilmer, Hiraoka, Kei, Inagaki, Akihito, Kamijima, Shuichi, Micewicz, Ewa, Gruber, Harry E., Robbins, Joan M., Jolly, Douglas J., McBride, William H., Iwamoto, Keisuke S., Kasahara, Noriyuki
Udgivet i Cancer Gene Ther (2014)

Combined Alloreactive CTL Cellular Therapy with Prodrug Activator Gene Therapy in a Model of Breast Cancer Metastatic to the Brain

af Hickey, Michelle J., Malone, Colin C., Erickson, Kate L., Lin, Amy, Soto, Horacio, Ha, Edward T., Kamijima, Shuichi, Inagaki, Akihito, Takahashi, Masamichi, Kato, Yuki, Kasahara, Noriyuki, Mueller, Barbara M., Kruse, Carol A.
Udgivet 2013

ET-60 ENHANCED THERAPEUTIC EFFICACY OF PRODRUG ACTIVATOR GENE THERAPY WITH A NON-LYTIC RETROVIRAL REPLICATING VECTOR (TOCA 511) COMBINED WITH RADIATION THERAPY IN EXPERIMENTAL GLIO...

af Takahashi, Masamichi, Valdes, Gilmer, Inagaki, Akihito, Kamijima, Shuichi, Hiraoka, Kei, Micewicz, Ewa, McBride, William H., Iwamoto, Keisuke S., Hermann, Kip, Collins, Sara, Tam, Quincy, Gruber, Harry E., Robbins, Joan M., Jolly, Douglas J., Kasahara, Noriyuki
Udgivet 2014

Retroviral replicating vector–mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity

af Hiraoka, Kei, Inagaki, Akihito, Kato, Yuki, Huang, Tiffany T., Mitchell, Leah A., Kamijima, Shuichi, Takahashi, Masamichi, Matsumoto, Hiroshi, Hacke, Katrin, Kruse, Carol A., Ostertag, Derek, Robbins, Joan M., Gruber, Harry E., Jolly, Douglas J., Kasahara, Noriyuki
Udgivet i Neuro Oncol (2017)

Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression

af Perez, Omar D, Logg, Christopher R, Hiraoka, Kei, Diago, Oscar, Burnett, Ryan, Inagaki, Akihito, Jolson, Dawn, Amundson, Karin, Buckley, Taylor, Lohse, Dan, Lin, Amy, Burrascano, Cindy, Ibanez, Carlos, Kasahara, Noriyuki, Gruber, Harry E, Jolly, Douglas J
Udgivet 2012

Epithelial Membrane Protein-2 (EMP2) Activates Src Protein and Is a Novel Therapeutic Target for Glioblastoma

af Qin, Yu, Fu, Maoyong, Takahashi, Masamichi, Iwanami, Akio, Kuga, Daisuke, Rao, Rajiv G., Sudhakar, Deepthi, Huang, Tiffany, Kiyohara, Meagan, Torres, Kathleen, Dillard, Christen, Inagaki, Akihito, Kasahara, Noriyuki, Goodglick, Lee, Braun, Jonathan, Mischel, Paul S., Gordon, Lynn K., Wadehra, Madhuri
Udgivet 2014