Epithelial Membrane Protein-2 (EMP2) Activates Src Protein and Is a Novel Therapeutic Target for Glioblastoma

Despite recent advances in molecular classification, surgery, radiotherapy, and targeted therapies, the clinical outcome of patients with malignant brain tumors remains extremely poor. In this study, we have identified the tetraspan protein epithelial membrane protein-2 (EMP2) as a potential target...

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Bibliographic Details
Main Authors: Qin, Yu, Fu, Maoyong, Takahashi, Masamichi, Iwanami, Akio, Kuga, Daisuke, Rao, Rajiv G., Sudhakar, Deepthi, Huang, Tiffany, Kiyohara, Meagan, Torres, Kathleen, Dillard, Christen, Inagaki, Akihito, Kasahara, Noriyuki, Goodglick, Lee, Braun, Jonathan, Mischel, Paul S., Gordon, Lynn K., Wadehra, Madhuri
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Molecular Bases of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022868/
https://ncbi.nlm.nih.gov/pubmed/24644285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.543728
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