Epithelial Membrane Protein-2 (EMP2) Activates Src Protein and Is a Novel Therapeutic Target for Glioblastoma

Despite recent advances in molecular classification, surgery, radiotherapy, and targeted therapies, the clinical outcome of patients with malignant brain tumors remains extremely poor. In this study, we have identified the tetraspan protein epithelial membrane protein-2 (EMP2) as a potential target...

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Detalhes bibliográficos
Main Authors: Qin, Yu, Fu, Maoyong, Takahashi, Masamichi, Iwanami, Akio, Kuga, Daisuke, Rao, Rajiv G., Sudhakar, Deepthi, Huang, Tiffany, Kiyohara, Meagan, Torres, Kathleen, Dillard, Christen, Inagaki, Akihito, Kasahara, Noriyuki, Goodglick, Lee, Braun, Jonathan, Mischel, Paul S., Gordon, Lynn K., Wadehra, Madhuri
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022868/
https://ncbi.nlm.nih.gov/pubmed/24644285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.543728
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